Juxtaposition of Ropivacaine with Bupivacine Hyperbaric Solutions for Spinal Anaesthesia in Elective Surgeries: A Prospective Randomized Double Blind Study
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2017, Vol 4, Issue 3
Abstract
Background: Baricity is the density of a substance compared to the density of human cerebrospinal fluid which used in anaesthesia to determine the manner in which a particular drug will spread in the intrathecal space and produce shorter duration of onset, greater level of blockade and fast recovery. Aim: To compare the clinical efficacy of hyperbaric Ropivacaine and Bupivacaine under spinal anaesthesia in terms of duration of onset, blockade and recovery. Settings and Design: Prospective, comparative and randomized double blind study. Methods and Material: About 80 patients from K S Hedge Medical College Hospital, NITTE University, Mangaluru, Karnataka, India were enrolled between January 2015 to August 2016 by random sampling method and divided into two groups as A and B. Group A received 3ml of 0.5% hyperbaric Bupivacaine and Group B received 3ml of 0.5% hyperbaric Ropivacaine. Subarachnoid block in L3-L4 space was performed by considering following parameters such as Onset and duration of block and recovery following injection. Statistical Analysis: Unpaired t test and Chi square test. P<0.05 was considered as statistically significant. Results: The duration of onset of sensory block to T10 with 0.5% hyperbaric Bupivacaine was 5.9±0.955 min when compared to 0.5% hyperbaric Ropivacaine which was 5.50±1.219 min with p value of 0.107. Conclusions: Hyperbaric Ropivacaine has showed more favourable profile than hyperbaric Bupivacaine in terms of shorter duration of onset, with higher level of sensory blockade and faster recovery.
Authors and Affiliations
Anil Shetty
Keywords
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- EP ID EP471512
- DOI 10.21088/ijaa.2349.8471.4317.11
- Views 100
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