Kavain analogues as potential analgesic agents.
Journal Title: Pharmacological Reports - Year 2012, Vol 64, Issue 6
Abstract
BACKGROUNd: Kavalactones are pharmacologically active compounds present in preparations of the root trunk of Piper methysticum Forst, known as kava. This work describes the analgesic activity of some synthesized analogues of synthetic kavain, which is the main component of kava.
Authors and Affiliations
Elaine Kormann, Patricia de Aguiar Amaral, Michele David, Vera Eifler-Lima, Valdir Cechinel Filho, Fátima Campos Buzzi
Keywords
Related Articles
- EP ID EP109305
- DOI -
- Views 73
- Downloads 0
Antioxidant agents and physiological responses in adult epileptic patients treated with lamotrigine.
Background: The aim of our research was to evaluate some biochemical changes in blood during lamotrigine (LTG) monotherapy of adult patients with epilepsy, and to check possible associations between typical selenium stat...
Welcome address.
Effect of cocaine on responsiveness of alpha(1)-adrenergic receptors in rat cerebral cortex: modulation by GABA-mimetic drugs.
We investigated the effects of single doses of cocaine (10 mg/kg, ip) and the gamma-aminobutyric acid (GABA)-mimetics tiagabine (10 mg/kg, ip) and vigabatrin (150 mg/kg, ip) injected separately or concomitantly with coca...
Apigenin inhibits TGF-β1 induced fibroblast-to-myofibroblast transition in human lung fibroblast populations.
Background: Flavonoids are dietary plant compounds suspected to reduce the incidence of chronic diseases in several regions of the world. Due to anti-allergic and anti-inflammatory activities, apigenin (4',5,7,-trihydrox...
Anticonvulsant and antidepressant activity of the selected terpene GABA derivatives in experimental tests in mice.
The present study was designed to investigate the central nervous system activity of terpene GABA (and piracetam) derivatives designated as BF-1, BF-2, BF-3, BF-4, BF-5, BF-6. We assessed their anticonvulsant activity in...