Ketorolac versus Magnesium Sulfate in Migraine Headache Pain Management; a Preliminary Study

Journal Title: Archives of Academic Emergency Medicine - Year 2017, Vol 5, Issue 1

Abstract

Introduction: Migraine is a common cause of emergency department (ED) visits. To date, there is no recommended drug of choice for pain management of these patients. In the present study, we aimed to evaluate the effectiveness of ketorolac and magnesium sulfate in this regard. Methods: This is a cross-sectional study performed on all 18 - 60 year-old patients, visiting two different EDs with complaint of moderate to severe migraine headache. Patients were treated with 30 mg ketorolac in one hospital and 1 gram magnesium sulfate in the other. Pain scores were assessed on arrival, 1 and 2 hours after drugs administration and quality of pain management was compared between two groups using SPSS 22. Results: 70 patients with the mean age of 36.4 ± 11.4 years were enrolled (51.4% male). The two groups were similar regarding baseline characteristics (p > 0.05). The improvement in pain score in magnesium sulfate group was greater than Ketorolac group after both one hour (6 vs 3; p < 0.001) and two hours (7 vs 5; p < 0.001). Conclusion: It seems that both ketorolac and magnesium sulfate are significantly effective in pain control of patients with migraine headache presenting to the emergency department. Magnesium sulfate was superior to ketorolac both one and two hours after drug administration.

Authors and Affiliations

Keywords

Related Articles

History and Structure of the Fourth Leading Emergency Medical Service in the World; a Review Article

Over forty-three years have passed since the foundation of pre-hospital emergency care system in Iran. Considering the changes that have taken place in recent years in pre-hospital emergency and limited studies in this a...

Conservative Management of Asymptomatic Pneumoperitoneum; Report of Two Cases

Peptic ulcer disease is a common gastrointestinal disorder, the prevalence of which has reduced in recent years due to effective new treatments. Peptic ulcer perforation is an emergent life-threatening condition that cau...

Accuracy of Ultrasonography in Confirmation of Adequate Reduction of Distal Radius Fractures

Introduction: The balance between revenue and cost of an organization/system is essential to maintain its survival and quality of services. Emergency departments (ED) are one of the most important parts of health care de...

Correlation of Hyperchloremic Metabolic Acidosis and Renal Function in Critically ill Patients of Emergency Department: an Observational Study

Introduction: Early detection is crucial for prompt management of acute kidney injury (AKI) patients in emergency department (ED). This study aimed to investigate the usefulness of hyperchloremic metabolic acidosis (HCMA...

The Relation of Q Angle and Anthropometric Measures with Ankle Sprain; a Case-control study

Introduction: Since most studies on ankle sprain are medical and sports-related and not much epidemiologic and etiologic data from the general population exist in this field, the present study evaluates the relationship...

Download PDF file
  • EP ID EP332721
  • DOI 10.22037/emergency.v5i1.11257
  • Views 163
  • Downloads 0

How To Cite

(2017). Ketorolac versus Magnesium Sulfate in Migraine Headache Pain Management; a Preliminary Study. Archives of Academic Emergency Medicine, 5(1), 2-. https://europub.co.uk/articles/-A-332721