Kinase Mutations as Predictive Biomarkers in Hematolymphoid Malignancies
Journal Title: Journal of Hematology & Thrombosis - Year 2015, Vol 1, Issue 1
Abstract
Targeted therapeutics against kinases has been employed in the clinic for over a decade. Their use of ten times requires concomitant molecular diagnostics evaluating the mutational status of the targeted kinases. While kinase mutations function as diagnostic and prognostic biomarkers in hematolymphoid malignancies, in this review, we focus on kinase mutations with predictive utility and their relevance to molecular diagnostics.
Authors and Affiliations
Benedict Yan
Keywords
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- EP ID EP246384
- DOI 10.13188/2380-6842.1000001
- Views 156
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