Klinefelter’s Syndrome Presenting with Recurrent Ischemic Strokes- A Case Report
Journal Title: Journal of Medical Sciences - Year 2017, Vol 20, Issue 2
Abstract
Introduction: Klinefelter’s syndrome (KS) is one of the most common chromosomal disorders associated with testicular dysfunction and male infertility with an incidence of 1:500 to 1:1000 in newborn male infants and prevalence of 0.2%.1-3 KS is the set of symptoms that result from the presence of two or more X chromosomes.3-4 KS is often associated with abdominal obesity, metabolic syndrome, type 2 diabetes mellitus and auto-immune diseases.1-3 Thrombotic risk in KS is comparable to that of inherited thrombophilias and estimated prevalence of thrombotic events like VTE and PE is similar in both.5-9 Case Report: We report a case of a 40-year-old male who presented to us with dysglycemia for control of blood glucose. He had history of recurrent ischemic strokes in past, primary infertility and hypertension. We diagnosed him with Klinefelter’s syndrome and attributed his presentation to metabolic syndrome and the hypercoagulable state associated with this syndrome. We managed this patient with aspirin, statins, insulin and testosterone.
Authors and Affiliations
Waris Purra, Javaid Rasool, Reyaz A Misgar, Arshad I Wani, M I Bashir, Shariq R. Masoodi
Keywords
Related Articles
- EP ID EP431673
- DOI -
- Views 37
- Downloads 0
Antibiotics in the NICU: In the absence of confirmed infection, higher rates of antibiotic use associated with worse outcomes in very-low-birth-weight babies.
All new-born babies are at risk of infection because their immune systems are not yet mature, and this is especially true for premature babies. This presumed presence of infection which is usually difficult to diagnose o...
Autophagy: Eat Yourself to Live
Autophagy is a metabolic process of consumption of the body's own tissues occurring in starvation and certain diseases. The field of autophagy has grown enormously over the past 1015 years, with rapid advances in our und...
CPC- Young Male With Oro-Genital Ulcers, Retroperitoneal Mass and Lymphadenopathy
A 18 year old male student was admitted to this hospital with painful oro-genital ulcers of mouth and severe odynophagia. He was in his usual state of health until approximately 25 days before admission when he develope...
Everolimus Induced Mucocutanious Toxicity
A 45 Years old female case of ductal cell carcinoma of the breast with ER/PR positivity diagnosed in the year 2009 and presently was on tamoxifen 20 mg once daily. Presented with bone pains and bone scan was showing incr...
Case of Large Brunner's Gland Adenoma
A 23-year-old man was admitted to the surgical ward with a two-month history of epigastric pain, abdominal discomfort, nausea and frequent bouts of vomiting. The Complete Blood Count (CBC) and biochemical investigations...