Knee Joint Neural Sources and Pathways and Their Osteoarthritis Pathogenic Linkages and Pain Control Implications
Journal Title: Journal of Orthopaedic Science and Research - Year 2024, Vol 5, Issue 2
Abstract
Background: Knee joint osteoarthritis, a widespread disabling disease with no known cause continues to produce considerable bouts of intractable pain and disability as a result of multiple disease associated health problems despite years of research. Aim: This paper examines if there is sufficient reason to believe one or more neural based abnormalities in the knee neural network may be involved or implicated in inducing and perpetuating at least some forms of knee joint osteoarthritis, but is often unrecognized and thus untreated or ignored. Methods: Peer reviewed data retrieved from several sources were examined to highlight and discuss the structural and functional nature of the knee joint nerves and their ramifications in various knee joint tissues, the spinal cord and central nervous system and motor control pathways. Results: Knee joint nerve pathways that are damaged or functioning abnormally can affect normal joint biomechanics, plus joint stability and thereby can influence the onset or perpetuation of knee joint pathology and exaggerated activation of pain fibers and cognitions. Conclusion: To improve the effectiveness of strategies designed to avert knee joint osteoarthritis pain and disability, attention to its possible ongoing neuropathology as well as possible declines in joint protective, perceptual and stability mechanisms in older vulnerable adults are indicated.
Authors and Affiliations
Ray Marks
Keywords
Related Articles
- EP ID EP740680
- DOI https://doi.org/10.46889/JOSR.2024.5205
- Views 49
- Downloads 1
Distinctive Skeletal Phenotype in Patients with Kniest Dysplasia
Background: A group of children presented with diverse forms of spine and joint pathologies in correlation with heritable bone disorders. Patients and Methods: Five children aged from 9 -13 years, presented with a con...
Distinctive Spine Deformities in Patients with Hurler (IH) and Hurler-Scheie (I-H/S) Syndrome
Purpose: Progressive kyphoscoliosis is not of uncommon occurrence in patients with MPSs. Cranio-cervical junction in patients with MPSs are under the threat of three life threatening elements, namely GAGs accumulation,...
Knee Joint Neural Sources and Pathways and Their Osteoarthritis Pathogenic Linkages and Pain Control Implications
Background: Knee joint osteoarthritis, a widespread disabling disease with no known cause continues to produce considerable bouts of intractable pain and disability as a result of multiple disease associated health probl...
Development and Validation of a Preclinical Canine Model for Delayed Onset Fracture-Related Infections
Background: Fracture-Related Infections (FRIs) are a challenging complication in orthopaedics. FRI incidence is considerably high, particularly in open fractures. FRI management typically involves multiple surgical inter...
An Unusual Case of Idiopathic Spinal Epidural Lipomatosis
An excess of adipose tissue buildup restricted to the lumbar and thoracic areas of the spine is the cause of spinal epidural lipomatosis. The etiology of spinal epidural lipomatosis can be broadly categorized based on fi...