L-Asparaginase Related Thrombotic Complications in Acute Lymphoblastic Leukemia Patients – An Experience from a Tertiary Care Centre
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 4
Abstract
Background: L- Asparaginase is commonly used chemotherapeutic agent in the treatment of acute lymphoblastic leukemia patients. The overall incidence of symptomatic venous thrombosis in acute lymphoblastic leukemia (ALL) varies from 1.5-11%. The risk of thrombotic complications in acute lymphoblastic leukemia (ALL) in children ranges from 1 to 37%. Most of the patients develop thrombosis related to L-asparaginase in the induction phase of chemotherapy. Purpose: To highlight the incidence of life threatening thrombotic complications related to L –Asparginase in acute lymphoblastic leukemia patients. Materials and Methods: This study was carried out retrospectively over a period of ten years. The data was taken from regional cancer registry and was compiled. Conclusions: Early identification and management of life threatening thrombotic complications associated with L-asparaginaseis necessary to improve survival outcome in Acute lymphoblastic leukemia patients.
Authors and Affiliations
Nusrat Bashir
Keywords
Related Articles
- EP ID EP493333
- DOI -
- Views 44
- Downloads 0
Evaluation of Dynamic Pulmonary Function Test in Overweight MBBS Students
Obesity is one of the most frequently found health risks and the prevalence of obesity is rapidly escalating globally in all age groups. Our aim was to determine and compare the possible alterations of pulmonary function...
Gestational Trophoplastic Disease in Babylon Maternity and Paediatrics Teaching Hospital a Prospective Study
Background: Gestational trophoblastic tumours arise from the cells of conception and form a range of related conditions, from the benign partial mole to the aggressive malignancies of choriocarcinoma and placental site t...
Comparison of the Patient’s Satisfaction, Aesthetic, Cost Effectiveness and Speech Problem in Hawley’s Retainer and Invisible (Clear) Retainer Question Based Study in Ahmadabad
Aim: To compare simple retainer (Hawley’s) and invisible (clear) retainer in people of Ahmadabad city. Material & Methodology: The present cross-sectional questioner study was conducted in Ahmadabad city. The study sampl...
Prognostic Value of Gravin Versus Survivin Gene Expression in a Cohort of Egyptian Patients with Adult Acute Myeloid Leukemia
Despite recent progress in diagnosis and management, acute myeloid leukemia still remains a highly fatal disease which invites the needs for accurate predictors of clinical outcome. The aim of the present study was to ex...
Post Traumatic Pneumocephalus- Clinical Profile in a Tertiary Care Centre
Introduction: The burden of head injury due to RTA on the society has now become a major cause of concern. The other main etiological factors contributing to head injuries include alcohol consumption, assault, fall from...