Laboratory surveillance of H1N1 swine influenza A virus infection in patients with severe acute respiratory illness (SARI)-an institutional study
Journal Title: International Journal of Medical Research and Review - Year 2016, Vol 4, Issue 2
Abstract
Introduction: Lower respiratory tract infections (LRTI) are a leading cause of death in developing countries and are also third leading cause of death worldwide. Influenza is an acute viral and highly contagious respiratory infection causing significant morbidity and mortality. The 2009, swine flu pandemic is caused by a novel reassorted H1N1 subtype of H1N1 influenza A virus. Objectives: The present laboratory study was conducted for the active surveillance of H1N1 swine influenza A virus infection in type C category of patients with Severe acute respiratory illnesses (SARI). Materials and Methods: In clinically suspected cases of swine flu, a total of 130 deep nasal / throat swabs were collected and inoculated into viral transport medium (Himedia labs ) and In the reference lab, samples were tested with Real time reverse transcriptase PCR for universal influenza A (inf A), swine influenza A (SWinfA) and swine H1 (SW H1) probes. Results: Among the total 130 samples, 32 are showing positive by Real time RT-PCR with a prevalence of 24.61%. In 0-5 age group, 10 were positive with prevalence of 62.5%. In total 66 were males with 12 positives (18.18 %), 64 were females with 20 positives (31.25%). Conclusion: H1N1 influenza A is a potentially infectious disease, which spreads by droplet infection, so laboratory based surveillance is necessary to know the intensity of infection , seasonal trends and epidemiological factors like variations according to gender, age and region; which is also helpful for local health authorities to take the appropriate control measures.
Authors and Affiliations
G N Ravi Prakash, K. Chakrapani, G. Swarna Latha, A. Surekha, Sailaja Sailaja, P. Sudhakar
Keywords
Related Articles
- EP ID EP227651
- DOI 10.17511
- Views 163
- Downloads 0
Antenatal diagnosis of oesophageal atresia with tracheoesophageal fistula with upper neck pouch sign-A radiological study
Oesophageal atresia is rare antenatal diagnosis due to absence of clinical and sonographic findings. On antenatal USG, the finding of an absent or small stomach bubble with polyhydramnios is considered suspicious of oeso...
Role of ca 19-9 as a tumor marker in diagnosis and prognosis of pancreatic carcinoma and cholangiocarcinoma (A study of 46 cases)
Introduction: Ca19-9 is currently the single most useful tumor marker for diagnosis and prognosis of pancreatic cancer and cholangiocarcinoma. Aim: The aim is to elucidate the importance of tumor marker ca 19-9 as a di...
Effect of music during exercise on rate of perceived exertion & mood status
Background: Music has been used in boosting performance during various exercise and sports events. This present study was planned to assess the effect of music on mood status and rate of perceived exertion during jumping...
Outcome after Interlocking intramedullary nailing of humeral shaft fractures
Introduction: Management of fractures of humeral shaft is always a challenging problem to deal with as they are very frequently associated with multiple injuries, leading to complications. Interlocking intramedullary nai...
Cerebral astroblastoma-a rare and elusive case
Background: Astroblastoma is rare neuroglial intracranial tumor most commonly occurring in the first three decades of life. Case report: A 5 year old female child presented with intermittent headache, diplopia and recurr...