LaCl3.7H20: An efficient catalyst for one-pot multi-component synthesis of 1,4-polyhydroquinoline derivatives through unsymmetrical Hantzsch reaction
Journal Title: Iranian Chemical Communication - Year 2017, Vol 5, Issue 3
Abstract
An efficient one pot multi component synthesis of 1, 4-Polyhydroquinoline derivatives through unsymmetrical Hantzsch reaction using lanthanum chloride heptahydrate (LaCl3.7H2O) from an aromatic aldehyde, ethyl acetoacetate, dimedone and ammonium acetate as a nitrogen precursor in ethanol at room temperature is described. In the present work we report lanthanum chloride heptahydrate remarkably non-toxic in nature and ease of handling we explored the utility of lanthanum chloride as a catalyst for the synthesis of 1, 4-polyhydroquinoline derivatives. We newly report p-N, N-dimethylamino-cinnamaldehyde and m-chlorobenzaldehyde for the synthesis of 1, 4-Polyhydroquinoline derivatives through unsymmetrical Hantzsch reaction and was characterized by IR and 1HNMR spectroscopic methods.
Authors and Affiliations
Abhijeet S. Somwanshi, Vishal U. Pandit, Akash D. Gholap, Rushikesh D. Ghogare, Shivaji S. Pandi
Keywords
Related Articles
- EP ID EP260244
- DOI -
- Views 126
- Downloads 0
Green synthesis of nano size CoFe2O4 using Chenopodium album leaf extract for photo degradation of organic pollutants
Green synthesis of nanoparticles makes use of environmental friendly, non-toxic and safe reagents. In this study, we synthesised CoFe2O4 in a green approach, using leaf extract of Chenopodium album. The structure of the...
Synthesis and characterization of derived imines from 4-imino-5,6,7,8-tetrahydro-1-benzothieno[2,3-d]pyrimidin-3(4H)-amine
The synthesis and characterization of derived imines from 4-imino-5,6,7,8-tetrahydro-1-benzo thieno[2,3-d]pyrimidin-3(4H)-amine 3 have been developed in three steps through the reaction of heteroaromatic o-aminonitrile 1...
ZnFe2O4 nanoparticle: Synthesis and photocatalytic activity under UV-vis and visible light
In the present work, the ZnFe2O4 nanoparticle has been successfully synthesized. The obtained sample was characterized by X-ray diffraction (XRD), emission scanning electron microscopy (FE-SEM) and its optical property w...
Magnetic nanoparticle immobilized N-propylsulfamic acid: The efficient, green and reusable nanocatalyst for the synthesis of substituted coumarins
N-Propylsulfamic acid supported onto magnetic Fe3O4 nanoparticles (MNPs-PSA) was investigated as an efficient and magnetically recoverable catalyst for the one-pot synthesis of substituted coumarins from the reaction of...
[BMIm]BF4-LiCl as an effective catalytic system for the synthesis of dicoumarols
A homogeneous ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate doped with LiCl ([BMIm]BF4-LiCl) was found as catalyst solvents for the synthesis of dicoumarols by the condensation of 4-hydroxycoumarin and aldeh...