Langerhans Cell Histiocytosis in a Patient with Lynch Syndrome (Hereditary Non Polyposis Colorectal Cancer)
Journal Title: Journal of Case Reports and Studies - Year 2015, Vol 3, Issue 3
Abstract
A fifty three year old white female smoker with Lynch Syndrome was receiving adjuvant chemotherapy for node positive caecal adenocarcinoma. Interval investigations demonstrated a second primary gastric cancer with bilateral pulmonary nodules of indeterminate significance. Lung biopsy revealed Langerhans cell histiocytosis (LCH). Our case highlights the importance of non-malignant pathology mimicking malignancy in a patient at risk of multiple primary tumors. To our knowledge an association between Lynch syndrome and LCH has not been previously documented, we review the literature.
Authors and Affiliations
Battley JE
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