Late Diagnosis, Smoking History and Socioeconomic Inequality in Gastric Carcinoma: A Decomposition Approach
Journal Title: International Journal of Cancer Management - Year 2017, Vol 10, Issue 3
Abstract
Background An association between cancer survival and socioeconomic status (SES) has been evaluated for many different cancers but calculating socioeconomic inequality in survival is very late. In this study we aimed to determine associations between socioeconomic inequality and survival risk factors in patients with gastric carcinoma (GC). Methods In this cross-sectional study, we enrolled 235 patients with confirmed GC. SES data were retrieved from three sources pathological records, official death certificates and telephone interviews. Polychoric correlation matrix was used to reduce the number of variables. Inequality was measured by concentration index (CI) and we decomposed CI to determine contribution in inequality. All analyses were performed by standard statistical software STATA (version 11.2). Results The overall CI for late diagnosis (2 stage onwards) and positive history of smoking were -0.020 (95% CI = -0.041 - 0.004) and -0.105 (95% CI = -0.110 - -0.076), respectively. Results of decomposition shows past medical history of gastrointestinal diseases (29%) and history of smoking (18%) have the largest contributions in inequality in GC survival. Conclusions Results of this study showed risk factors in GC survival such as smoking, having a past medical history of gastrointestinal diseases and late diagnosis are more prevalent among people of lower SES.
Authors and Affiliations
Yousef Veisani, Ali Delpisheh
Investigation of the Association of HOTAIR Single Nucleotide Polymorphisms and Risk of Breast Cancer in an Iranian Population
Background: Long non coding RNAs (lncRNAs) are of functional non coding RNAs which have been shown to be involved in several important pathways in cancer development and progression. Among them is Hox transcript antisens...
Phytochemicals in Cancer Prevention: A Review of the Evidence
Context: Cancer generally is considered as a neoplastic disease with particular causative and etiologic factors as well as protective elements. Although it has remained difficult to treat, it is preventable. Recently, th...
Evaluation of the Gene Expression of the Cytoprotective Proteins in Response to Daunorubicin in U937 Cells
Background: Daunorubicin (DNR) is capable of killing the human acute myeloid leukemia cells through apoptosis or necrosis with arresting cell cycle and various mechanisms. The response of AML cells to DNR associated with...
Clinical Value of Human Leucocyte Antigen G (HLA-G) Expression in the Prognosis of Colorectal Cancer
Objectives Overexpression of human leukocyte antigen G (HLA-G) in several malignant tumors has been reported. The aim of our study was to investigate HLA-G expression in colorecta...
Modified Intermediate-Dose Cytarabine Combined with Daunorubicin Induction and Re-Induction Protocol Use in Patients with Acute Myeloid Leukemia
Background A prospective study was conducted to investigate the response rate of patients newly diagnosed with acute myeloid leukemia (AML) to modified intermediate-dose cytarabin...