LATE ONSET ADVERSE DRUG REACTIONS OF STAVUDINE IN COMPARISON WITH ZIDOVUDINE; REASON FOR DISCONTINUATION
Journal Title: IJSR-International Journal Of Scientific Research - Year 2018, Vol 7, Issue 6
Abstract
The main objective of study is to compare the adverse drug reactions (ADRs) of Zidovudine and Stavudine containing regimens. It is a prospective observational study conducted in the ART centre of a tertiary care teaching hospital in central India. The data collected were recorded on standard ADR reporting forms. Standard scales were used for assessment of ADRs. In twelve months duration total 263 patients on ART were observed for ADRs. 128 patients on Stavudine based regimen and 135 patients were on Zidovudine based regimen. Total 72 ADRs detected in 68 patients. Incidence of ADRs was more in Zidovudine based regimen. Zidovudine associated with early and mild ADRs while Stavudine associated with late and distressing ADRs. Considering the magnitude of ADR related problems, results support the discontinuation of Stavudine based regimens.
Authors and Affiliations
Dr. Sandeep Kumar Adwal, Dr. B. L. Bamboria, Dr. Ashutosh Chourishi, Dr. Aditya Bamboria
Keywords
Related Articles
- EP ID EP510207
- DOI -
- Views 47
- Downloads 0
Occurrence of virulence markers and profile of antimicrobial susceptibility of uropathogenic E.coli in central India.
Uropathogenic Escherichia coli, the most frequent pathogens in acute urinary tract infections, take advantage of assortment of virulence properties. Bacterial adherence to and colonization of the urinary tract by UPEC st...
LYMPHOMA OF TESTIS-A RARE CASE REPORT
Primary testicular lymphoma constitutes 1-2% of Non-Hodgkin's lymphomas affecting elderly men >60 years of age. The most common histologic type is Diffuse large B cell lymphoma (DLBCL). Differential diagnosis includessem...
LIBRARY AUTOMATION IN ORDER TO DESIGN LIBRARIES FOR THE NEEDS OF FUTURE USERS
This paper explains that 'Library Automation in Order to Design Libraries for the Needs of Future Users'. The Integrity of Digitized Information Content The notion of 'content' as text is familiar to all information user...
Urinary Tract Infection (UTI) In the Elderly - A Clinical and Microbiological Study
Introduction: Urinary tract infections (UTIs) are more common in geriatrics due to physiological alterations or pathological conditions. Urinary tract infection in the elderly poses a very serious problem. Aim of the stu...
SOCIOECONOMIC STATUS AMONG INFERTILE COUPLES
Introduction: Infertility is the common health problem in developing countries like India. Infertility has been associated with the various socioeconomic condition and anthropometric parameters. It is the matter of socia...