LEPTADENIA HASTATA (PERS) DECNE: PHYTOCHEMICAL, PHARMACOLOGICAL, BIOTECHNOLOGICAL, BOTANICAL, TRADITIONAL USE AND AGRONOMICAL ASPECTS
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2018, Vol 5, Issue 6
Abstract
Leptadenia hastata (Pers.) Decne (Asclepiadaceae), it is a traditional tropical plant species with curative potentials. Many of this medicinal plants species are used as spices, foods and medicinal purposes. It is widely used in traditional medicine to treat various ailments such as cough, dyspnea, and fever, burning sensation, night blindness, cancer, hypertension diabetics, gonorrhea, catarrh, sex potency, wound healing, inflammation and dysentery. The therapeutic potential of this herb is as a result of the presence of diverse bioactive compounds such as α-amyrin, β-amyrin, ferulic acid, luteolin, diosmetin, rutin, β-sitosterol, stigmasterol, hentriacontanol, a triterpene alcohol simiarenol, apigenin, reticulin, deniculatin, and leptaculatin. However, most of the studies on Leptadenia hastata are restricted to crude extracts, and many biologically active compounds are yet to be identified in order to claim the traditional uses of this plant as acclaimed by the herbal and traditional practitioners. The plant is threatened and endangered because of overexploitation, unscientific harvesting, and habitat loss. The increased demand from pharmaceutical, nutraceutical, academia and veterinary industries has prompted its large-scale propagation. However, its commercial cultivation is hampered because of the non-availability of genuine planting material and the lack of knowledge on its agronomical practices. However there is a need for micro propagation technique to obtain the right type of Leptadenia hastata through the knowledge of biotechnological approaches can guaranty conservation as well as increased metabolite production from Leptadenia hastata. This review summarizes scientific information on the botanical, agronomical, phytochemical, pharmacological, and biotechnological aspects of Leptadenia hastata. This knowledge of information will certainly provide better utilization of this industrially important herb towards the discovery of lead drug for diseases and ailments. However, most studies of this plant species are restricted to crude extracts, which gives room for yet unidentified compounds to appreciate the claim to evidence the base use of the plant by the traditional medical practitioners.
Authors and Affiliations
Isaac John Umaru
Keywords
Related Articles
- EP ID EP637700
- DOI -
- Views 127
- Downloads 0
INTRANASAL MIDAZOLAM, FENTANYL AND DEXMEDITOMITIDINE AS A PREMEDICATION IN PEDIATRIC SURGICAL PATIENTS
Background: For providing premedication to pediatric surgical patients, various drugs and many routes have been studied. Intranasal route is one of them. It’s one of the preferred routes because of the ease of administra...
EFFECT OF ALLIUM SATIVUM ESSENTIAL OIL ON THE GLYCEMIC CONTROL AND HYPERLIPIDEMIA IN TYPE 2 DIABETES MELLITUS SUBJECTS
Background: Allium sativum (AS) is used as herbal medicine since time immemorial. Allium sativum has shown anti- hyperglycemic, anti oxidant, anti cancer, and anti atherogenic activity. Objective: To analyze the glycemic...
APPLICATION OF 3D PRINTING IN DENTISTRY- REVIEW
Over the past 30 years, 3D printing and prototyping has gained popularity within medical and dental profession and among patients alike. Three-dimensional (3D) printing is an additive manufacturing methods in which 3D ob...
ANTIPHOSPHLIPIDS ANTIBODIES IN CHRONIC HEPATITIS B PATIENTS PRESENTING AT A TERTIARY CARE HOSPITAL OF SINDH
Objective: To investigate the antiphospholipid antibodies in chronic hepatitis B patients presenting at a tertiary care hospital of Sindh. Study design: Case control study. Place and Duration: Department of Medicine, Lia...
ABO BLOOD TYPES OF BABCOCK UNIVERSITY STUDENTS, NIGERIA AND THEIR LINK WITH HELICOBACTER PYLORIINFECTION
Five millilitres (5ml) of venous whole blood was collected from one hundred and eighty three students made up of 93(50.8%) male and 90(49.2%) female students of Babcock University, Ilishan Remo randomly selected across v...