Lesions responsible for phonological paraphasia and auditory–verbal short-term memory disturbances in aphasia
Journal Title: Acta Neuropsychologica - Year 2012, Vol 10, Issue 1
Abstract
[b]Background: [/b]Fluent speech with phonological paraphasia is characteristic of conduction aphasia and Wernicke’s aphasia. Phonological paraphasia is characterized by speech sound errors that still convey the intended meaning. Some patients with phonological paraphasia show auditory–verbal short-term memory (STM) disturbances. However, it is not certain that phonological paraphasia results from such memory disturbances. [b]Material/Methods:[/b] We compared the overlapping lesions of 30 patients with phonological paraphasia, with the most relevant lesions of 38 patients with auditory–verbal STM disturbances (digit span and letter span). [b]Results: [/b]The results showed that the overlapping lesions of patients with phonological paraphasia were located in the subcortical white matter in the left supramarginal gyrus, regardless of the type of aphasia. The lesions most relevant to digit span disturbances were located in the subcortical white matter in the left angular gyrus, and those most relevant to letter span disturbances were located in the left superior temporal cortex. Although the lesions most relevant to phonological paraphasia and those most relevant to auditory–verbal STM disturbances were closely located, they did not correspond. [b]Conclusions: [/b]These findings suggest that the cause of phonological paraphasia is not auditory–verbal STM disturbances but non-conduction of a large amount of information through underlying white matter lesions, and that two auditory–verbal STM storage sites exist in the human brain.
Authors and Affiliations
Fumiko Anzaki, Yoshimi Suzukamo, Yutaka Oouchida, Takeo Kondo, Shin-Ichi Izumi
Keywords
Related Articles
- EP ID EP55388
- DOI -
- Views 122
- Downloads 0
The impact of therapist training in interpersonal communication on rehabilitation outcome for traumatic brain injury patients
The aim of the study was to evaluate the effectiveness of rehabilitation of traumatic brain injury (TBI) patients when conducted by therapists who had participated in a training program on effective patient communication...
STROKE IMPACT ON THE COGNITIVE FUNCTIONS OF MOROCCAN NEURO-LESIONED PATIENTS IN THE GHARB REGION
Stroke (ischemic and hemorrhagic stroke) is a sudden-onset neurological deficit resulting from focal vascular lesions. This is due to a clot-induced obstruction of a vessel (ischemic stroke) or a rupture of a vessel caus...
MEMORY IMPAIRMENT IN DEMENTIA WITH LEWY BODIES RELATIVE TO ALZHEIMER’S DISEASE AND PARKINSON’S DISEASE WITH DEMENTIA
The cognitive profiles of patients with dementia with Lewy bodies (DLB) and Parkinson’s disease with dementia (PD-D) are quite similar, though different from Alzheimer’s disease. However, studies comparing the memory per...
HEALTH-RELATED QUALITY OF LIFE IN OBESITY
Obesity is a multifactor, chronic metabolic disease involving an excessive build-up of adipose tissue in the body. The severity of obesity is measured with the Body Mass Index (BMI). A BMI within the range of 25-29.9 kg/...
THE STRATEGIC APPROACH TO THE REHABILITATION OF PATIENTS WITH LOCKED IN SYNDROME
[b]Background. [/b]This article presents an evaluation of the strategic approach to managing rehabilitation for patients with cervical spinal cord injuries and locked in syndrome. Consistent pursuit of concrete and expli...