Let-7d A Novel Regulator in Oral Squamous Cell Carcinoma.
Journal Title: International Journal of Dental Science and Innovative Research (IJDSIR) - Year 2019, Vol 2, Issue 2
Abstract
Oral squamous cell carcinoma (OSCC), is the sixth most preva¬lent cancer worldwide and accounts for approximately 8-10% of all cancers in Southeast Asia. Malignant transformation of mucosal lesions predispose to oral cancer. The World Health Organization (WHO) defined these lesions as “potentially malignant disorders (PMD)”. Betel quid chewing, alcohol consumption and smoking habits have been indicated to increase the risk of malignant transformation. The number of new OSCC cases is increasing day by day worldwide, especially in the developing countries, and the prognosis remains poor in spite of recent advances in the diagnostic and therapeutic modalities due to expensive diagnosis. 50% of the OSCC patients die or complications within 5 years under current therapies. To increase patient survival rate, investigations elucidating the mechanisms of tumorigenesis in OSCC are in need. Some studies have suggested that tumor initiating cells (TICs) are responsible for tumor progression as well as recurrence after the chemotherapy.
Authors and Affiliations
Dr. Shaista Suhail
Keywords
Related Articles
- EP ID EP579866
- DOI -
- Views 63
- Downloads 0
Comparative evaluation of fluoride releasing hydrophilic pit and fissure sealant with a highly filled nano-hybrid pit and fissure sealant in the prevention of dental caries in children- an in-vitro study.
Purpose: To determine the degree of microleakage of fluoride releasing hydrophilic pit and fissure sealant (Group I) with a highly filled nano-hybrid pit-and-fissure sealant (Group II) using dye penetration method. Mater...
Radix Entomolaris and Its Anatomical Variations - A Review
The basic prerequisites for successful endodontic treatment are firstly a comprehensive knowledge on the root canal anatomy and proper identification of all the canals, meticulous chemo-mechanical preparation followed by...
Electromyography of the Masticatory Muscles – A Quick Glance.
The knowledge of masticatory function and its relationship with craniofacial morphology is essential to the field of orthodontics. Electromyography has been used to assess the muscle function of the masticatory muscles b...
Use of an Impacted Post and Polyethylene Tube with Sutures as Fixation Methods during Vestibuloplasty Procedures
Background and Objectives: The purpose of this study was to clinically evaluate the efficacy of impacted post in terms of vestibular depth and relapse in comparison with polyethylene tubes with sutures as the fixation me...
Effect of Various Esthetic Clasp Materials on the Retentive Capacity of Circumferential Clasp Assembly - An Invitro Study.
Introduction: Retention achieved in removable partial dentures through Cobalt Chromium clasp assemblies has shown to be clinically successful. However, due to poor aesthetics, attention has been drawn towards developing...