Leukemia inhibitory factor, glycodelin, and HOXA-10 in gestational diabetes
Journal Title: Clinical and Experimental Obstetrics & Gynecology - Year 2019, Vol 46, Issue 4
Abstract
Purpose of investigation: The authors aimed to localize glycodelin, leukemia inhibitory factor (LIF), and HOXA-10 in term placentas and study the relationship between these markers and maternal gestational diabetes. Materials and Methods: Following labor, placentas from 12 pregnant women with gestational diabetes and 15 healthy pregnant women were collected, fixed, and paraffin-embedded, and immunohistochemical studies were performed. Two independent researchers examined the specimens under light microscopy. Immunoreactive scores were calculated and compared. Results: Glycodelin and HOXA-10 were stained in the decidua, and LIF was stained both in the trophoblast and in the decidua of term placentas. The three markers’ immunoreactive scores were not different between pregnant women with gestational diabetes and the healthy controls. Conclusion: Glycodelin and HOXA-10 were produced by maternal decidual cells; LIF was produced by both trophoblasts and maternal decidual cells. Glycodelin, HOXA-10, and LIF are not related to the pathophysiology of gestational diabetes.
Authors and Affiliations
Y. Aydin, S. Uludağ, A. Atis
Keywords
Related Articles
- EP ID EP672750
- DOI 10.12891/ceog4532.2019
- Views 57
- Downloads 0
Improvement of concomitant symptoms of pelvic organ prolapsed with applied pessary
Introduction: A common disorder among elderly ladies which causes urinary, gastrointestinal, sexual, and local symptoms is pelvic organ prolapse (POP). Two methods that include surgical and non-surgical (conservative) fo...
Uterine manipulator – low budget option
In these report the authors describe one simple option to build a uterine manipulator with disposable materials used commonly in medical practice: a foley cateter, a 60 cc syringe, and a hysterometer. They believe this m...
Congenital unilateral pulmonary hypoplasia presenting as cardiac dextroposition on prenatal ultrasonography
Objective: To report a case of congenital right pulmonary hypoplasia presenting as cardiac dextroposition on prenatal ultrasonography. Case Report: A 29-year-old woman with fetal dextroposition visited this institution a...
Use of sympathomimetic amines to correct premenstrual urticaria and anaphylaxis
Purpose: To see if the use of sympathomimetic amines, which have been shown to treat cases of hives, can help prevent cyclical urticaria and anaphylaxis associated with the late luteal phase that was resistant to standar...
Does the placental strain ratio correlate with the umbilical artery Doppler values?
Objective: The aim of this study is to reveal whether there is any relationship between strain elastography (SE) values and Doppler ultrasonography (US) findings, and to investigate the availability of SE in early diagno...