Level of High-Sensitivity C-Reactive Protein Assay to Evaluate Risk in Follow-Up Patients with Acute Coronary Syndrome
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 3
Abstract
Introduction: Among currently recognized inflammatory markers numbers of considerations favor high-sensitivity C-reactive protein (Hs-CRP) as a potentially useful predictor of prevalence and incidence of cardiovascular diseases. Clinical interest in these markers has also focused on their potential utility in predicting future cardiovascular events and thereby in patient’s management. Purpose of study: The purpose of the study was to determine the mean level of Hs-CRP assay in patients of acute coronary syndromes and corelation of Hs-CRP with two or more major risk factors and to correlate the level of Hs-CRP and cardiac events in patients of acute coronary syndromes during follow-up of a specified period of 6 months. Materials and Methods: Present study had been carried out in the Department of Medicine, Gajra Raja Medical College and associated Hospital, Gwalior, Madhya Pradesh, India, from January 2004 to September 2005. This was a prospective observational study. The targeted populations were 30 cases with acute coronary syndromes of both sexes. Results: The study was statistically insignificant in reference to various major cardiac events compared to various levels of Hs-CRP. ST elevation myocardial infarction (MI) was the most prevalent acute coronary syndrome. Most of the risk factors show their association with the moderate risk level of Hs-CRP, i.e., 1.0–3.0 mg/L, followed by high-risk levels, i.e., >3.0 mg/L, followed by low-risk levels, i.e., <1.0 mg/L. Post MI/angina was the major cardiac event that highest number of patients developed, during the follow-up period of 6 months. Conclusion: No statistically significant association of various risk factors with Hs-CRP was observed in patients of acute coronary syndromes. No statistically significant association of Hs-CRP levels with major cardiac events was appreciable in patients of acute coronary syndrome in a follow-up period of 6 months.
Authors and Affiliations
Himanshu Mathur, Jitendra Kumar Jatav
Keywords
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