Level of S100B protein, neuron specific enolase, orexin A, adiponectin and insulin-like growth factor in serum of pediatric patients suffering from sleep disorders with or without epilepsy.
Journal Title: Pharmacological Reports - Year 2012, Vol 64, Issue 6
Abstract
Paroxysmal sleep disorders in children are important from both pathophysiological and clinical point of view. Correct diagnosis is crucial for further management. The aim of the present study was to identify peripheral markers of paroxysmal sleep disorders in children, which could improve diagnostics of these disorders. We compared serum levels of several putative biomarkers of neurological disorders, such as S100B protein, neuron specific enolase (NSE), orexin A, adiponectin, and insulin-like growth factor 1 (IGF-1) in pediatric patients suffering from sleep disturbances with those who additionally to parasomnia revealed also epilepsy.
Authors and Affiliations
Marek Kaciński, Bogusława Budziszewska, Władysław Lasoń, Anna Zając, Barbara Skowronek-Bała, Monika Leśkiewicz, Alicja Kubik, Agnieszka Basta-Kaim
Keywords
Related Articles
- EP ID EP140991
- DOI -
- Views 114
- Downloads 0
Repeated administration of caffeine induces either sensitization or tolerance of locomotor stimulation depending on the environmental context.
Caffeine is the psychostimulant substance consumed in greatest quantities in the world. The repeated administration of psychostimulants can either decrease or increase the drug effect, inducing tolerance or sensitization...
Opposite effects of beta amyloid on endothelial cell survival: role of fibroblast growth factor-2 (FGF-2).
Amyloid beta-peptides (Abeta) aggregate during Alzheimer's disease contributing to the development of the pathology. At micromolar concentration Abeta is toxic and accumulates in neurons and in the vasculature. However,...
4-Thio-uridylate (UD29) interferes with the function of protein -SH and inhibits HIV replication in vitro.
In this short communication, it is shown that 4-thio-uridylate (s(4)UMP, designated as UD29) inhibits glyceraldehyde 3-phosphate dehydrogenase (GAPDH), suggesting that the enol-form of the thiolated nucleotide may interf...
Effects of standard heparin and low-molecular-weight heparins on the formation of murine osteoclasts in vitro.
Long-term administration of heparin can lead to development of osteoporosis. The aim of the present study was to examine the effects of standard heparin and low-molecular-weight heparins (nadroparin, enoxaparin, parnapar...
Novel variant of CYP2D6*6 is undetected by a commonly used genotyping procedure.
We report the identification of a novel and defective variant of the gene encoding cytochrome P450 2D6 (CYP2D6). This novel variant is a subtype of CYP2D6*6 that was undetected by a commercially available 5' exonuclease-...