LH/FSH, BMI and Clinical Profile in Polycystic Ovarian Syndrome: A Correlative Study
Journal Title: International Journal of Biochemistry Research & Review - Year 2016, Vol 9, Issue 1
Abstract
Background and Objectives: Polycystic ovarian disease (PCOS) is probably the most prevalent endocrinological disorder affecting females and is the most common cause of menstrual disturbance during the reproductive age. It is characterized by polycystic ovaries on ultrasound and/or clinical and biochemical signs and symptoms of hyperandrogenism and/or oligo- anovulation. Therefore, this study was designed to determine relationship among LH/FSH ratio, BMI and the clinical profile of females suffering from PCOS. Materials and Methods: Blood samples from 50 study subjects were taken after getting informed consent for hormone profile (FSH and LH) by ELISA kit of Kamiya Biomedical company. Body Mass index (BMI) and Ultra-sonogram related findings of polycystic ovarian syndrome patients were recorded. Statistical analysis was done by using SPSS-20. Results: LH/FSH values were significantly higher among infertile and fertile females (P=0.05). BMI was also significantly correlated statistically in female patients with and without hirsutism (P=0.005). BMI (P=0.00) and LH/FSH (P=0.004) were also found to be associated significantly with obesity in patients with PCOS. Conclusion: Since FSH was significantly correlated with obesity and infertility while BMI was associated with obesity and hirsutism among the clinical profiles, lifestyle interventions to decrease the overweight and obesity would be able to reduce the unwanted clinical symptoms of infertility and hirsutism in females with polycystic ovary syndrome.
Authors and Affiliations
Hifsa Mobeen, Hamdan Hamid, Almina Shafiq, Muhammad Adil, Noshin Wasim Yousuf
Keywords
Related Articles
- EP ID EP351104
- DOI 10.9734/IJBCRR/2016/21676
- Views 121
- Downloads 0
Assessment of Some Biochemical Oxidative Stress Markers in Type II Diabetics and Non-diabetics with Chronic Periodontitis
Aims: Comparative assessment of some biochemical oxidative stress markers in Type II diabetics and non-diabetics with chronic periodontitis. Study Design: The cross sectional study groups were clinically evaluated and th...
Multi-residue Pesticides in Conventional and Organic Orange
A monitoring project for pesticide residues in orange samples in Al-Tamer vegetables market, Riyadh was conducted. A total of 144 samples of organic and non-organic orange were collected according to the Codex Alimentari...
Standardization of Protocol for Best Blending Ratio of Papaya cv. Red Lady and Guava cv. Allahabad Safeda Fruit Pulp for Preparation of Fruit Bar
The papaya and guava pulps were blended in the ratios of 100:0, 80:20, 60:40, 50:50 and 40: 60 in preparation of fruit bar and physicochemical analysis and sensory attributes were evaluated at zero (initial), 30 and 60 d...
Weekly Occurrence of Gymnodinium catenatum and Paralytic Shellfish Poisoning in the Mediterranean Shore of Morocco
Weekly monitoring for the presence of Gymnodinium catenatum and PSP toxins in mussels (Mytilus galloprovinciallis) harvested on the growing site in Fnideq on the Mediterranean Moroccan coast was carried out from 2010 unt...
Biochemical Evaluation of the Antioxidant Nutrients on Blood Rheology among Prediabetics
Background: Oxidative stress is involved in the developing of several diseases including diabetes followed by the majority of severe acute illness and/or contra complications. Current studies indicated increasing plasma...