Light Chain Myeloma induced Severe Hypertriglyceridemia
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 3
Abstract
Hyperlipidemia is very common in general population and incidence has further increased in recent years. Evaluation of patient presenting with lipid disorders is essential to obtain a definite diagnosis to prevent complications, and apply the most appropriate treatment. An isolated elevation in triglyceride levels may be caused by a primary disorder of lipid metabolism like familial hypertriglyceridemia. It may also arise secondary to a number of conditions like diabetes mellitus, alcohol intake, hypothyroidism, drugs, infections and nephrotic syndrome. Herein, we describe a case of secondary hypertriglyceridemia leading to Nonalcoholic Steatohepatitis (NASH) in a young female which was attributed to Multiple Myeloma (MM). Significant reduction in triglyceride levels after starting anti-myeloma therapy established their relation. This is the first case of light chain myeloma causing severe secondary hypertriglyceridemia.
Authors and Affiliations
Shafeeque Rahman, Prabhat Kumar, Subodh Kumar Mahto, Rajinder Singh Tonk, Rajesh S Taneja
A 14-year Follow-up of Resin Composite Occlusal Restorations: Split Mouth Randomised Clinical Trial and Wear Evaluation by Optical Coherence Tomography
ABSTRACT Introduction: The search for restorative materials with clinical longevity has led to modifications in the composition of the resin composites. Aim: To evaluate the clinical performance and the occlusal wear of...
Serum Vitamin D Level as a Risk Factor for Female Genital Tuberculosis (FGTB)
Introduction: Vitamin D is now known to be essential to Mycobacterium tuberculosis containment and killing through activation of 25-hydroxyvitamin-D receptors (VDRs) present on all immune cells or obtained from dietary f...
Educational Intervention to Increase Hepatitis B Vaccination among Housekeeping Staff
ABSTRACT Introduction: Hepatitis B Virus (HBV) causes acute and chronic liver disease which can progress to cirrhosis and hepatocellular carcinoma. The seroprevalence in India is about 2% to 8%. When compared to general...
A Prospective Study of Routine Screening of Hypothyroidism in Antenatal Patients and their Outcome with Levothyroxine Treatment
Introduction: Pregnancy with hypothyroidism is associated with significant maternal, fetal and neonatal complications. Early diagnosis and treatment can effectively reduce such complications. Aim: To find out the complic...
A Swimmer in a Sea of Tumour
Letter to Editor