Lipedema: A Clinical Challenge-revisited
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 5, Issue 11
Abstract
Lipedema is a disfiguring disorder with abnormal and progressive deposition of adipose tissue in the hips and lower extremities almost exclusively occurring in women. There is a hereditary tendency and a substantial variability in disease severity. Lipedema is often misdiagnosed as lymphedema or morbid obesity. The etiology and pathogenesis are not understood. Early diagnosis and treatment are critical to minimize physical and psychological morbidity. The diagnosis is usually made by history and clinical examination. Non-invasive imaging techniques such as computed tomography or magnetic resonance can differentiate lipedema from other causes of edematous lower extremities. Lymphoscintigraphy may be helpful in cases which are associated with lymphedema (lipo-lymphedema). Management with manual lymphatic drainage and compression therapy are considered the most appropriate treatment. Use of conventional liposuction is controversial since it may further damage the lymphatic vessels. Newer techniques such as tumescent micro annular laser assisted liposuction and water jet-assisted liposuction have shown some promising results. Variety of other surgical procedures combined with manual lymphatic drainage and tailored post-surgical care are under investigation.
Authors and Affiliations
Mohammad Omaira, Avanti Mehrotra, Margaret J. Fankhauser, Borys Hrinczenko, Nikolay V. Dimitrov
Keywords
Related Articles
- EP ID EP347065
- DOI 10.9734/BJMMR/2015/13894
- Views 55
- Downloads 0
Analyze of Risk Factors Affecting the Outcomes of Docetaxel-prednisone Combination in the Treatment of Metastatic Castration-resistant Prostate Cancer
Objective: To analyze potential factors affecting the outcomes of docetaxel and prednisone (DP) combination therapy in patients with castration resistant prostate cancer (CRPC). Methods: A total of 272 patients were trea...
Estradiol and/or Ibandronate Therapy Ameliorates Oxidative Status in Livers of Ovariectomized Rats
Background: Overiectomized rats suffer from osteoporosis that mainly results from oxidative stress (OS). Studies revealed that the levels of antioxidant enzymes, such as superoxide dismutase (SOD), glutathione peroxidase...
A 66 Patient Multi-Institution Phase IV Post-Authorization Surveillance of ProThelial™ (High Potency Polymerized Cross-linked Sucralfate) -Single Agent Efficacy for the Prevention and Rapid Reversal of Chemo-radiation Induced Oral, Esophageal and Intestinal Mucositis
Background: Standard potency sucralfate is not recommended by most clinical guidelines for prevention or treatment of oral and intestinal mucositis. However, its polymerized cross-linked (thereby high potency) formulatio...
Metabolic Syndrome in a Sub-population of Geriatric Nigerians in a Primary Care Clinic of a Tertiary Hospital in South-Eastern Nigeria
Background: Research studies have shown that age is an independent risk factor for metabolic syndrome (MetS). However, as eco-demographic structure and function of Nigeria changes, geriatric Nigerians tend to adopt lifes...
Assessment of Value of Fatigue Severity and Symptoms in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Fibromyalgia
Background and Objective: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) remains a challenge for health care professionals because of its complex pathogenesis. Scales and questionnaires have been developed i...