Lipedema: A Clinical Challenge-revisited
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 5, Issue 11
Abstract
Lipedema is a disfiguring disorder with abnormal and progressive deposition of adipose tissue in the hips and lower extremities almost exclusively occurring in women. There is a hereditary tendency and a substantial variability in disease severity. Lipedema is often misdiagnosed as lymphedema or morbid obesity. The etiology and pathogenesis are not understood. Early diagnosis and treatment are critical to minimize physical and psychological morbidity. The diagnosis is usually made by history and clinical examination. Non-invasive imaging techniques such as computed tomography or magnetic resonance can differentiate lipedema from other causes of edematous lower extremities. Lymphoscintigraphy may be helpful in cases which are associated with lymphedema (lipo-lymphedema). Management with manual lymphatic drainage and compression therapy are considered the most appropriate treatment. Use of conventional liposuction is controversial since it may further damage the lymphatic vessels. Newer techniques such as tumescent micro annular laser assisted liposuction and water jet-assisted liposuction have shown some promising results. Variety of other surgical procedures combined with manual lymphatic drainage and tailored post-surgical care are under investigation.
Authors and Affiliations
Mohammad Omaira, Avanti Mehrotra, Margaret J. Fankhauser, Borys Hrinczenko, Nikolay V. Dimitrov
Uncommon Sites for Body Stuffing: A Literature Review
Introduction: ‘‘Body stuffing’ refers to concealment of illegal drugs within the human body to avoid arrest. Emergency physicians and law enforcement authorities should be aware of uncommon sites of concealment used to a...
CYP17, CYP19, and NQO1 Genetic Polymorphisms and Breast Cancer Susceptibility in Young Women in Brazil
Aims: Breast cancer is the most common cancer in women worldwide, being exposure to estrogens the acknowledged main risk factor. CYP17, CYP19 and NQO1 are enzymes involved in the estrogen metabolism, so their polymorphis...
Colon Obstruction and Gradual Regression of Giant Pseudopolyps in Inflammatory Bowel Disease
Inflammatory pseudopolyps associated with inflammatory bowel disease occur on inflamed colon mucosa due to the regeneration and healing of ulcerated epithelium. They are classified as giant when they are over 1.5-cm in d...
Comparative Evaluation of Smear Layer Removal Efficacy Using QMix 2in1, Chitosan, Smear Clear and Glyde
Aim and Objective: The effects of four endodontic irrigants and on a smear layer created by hand and rotary instrumentation were evaluated in vitro in the middle and apical thirds of root canals. Materials and Methods: F...
Prevalence of Diabetes Mellitus in a Population-Based Sample of Adults in Tirana, Albania
Aims: Our aim was to assess the prevalence of diabetes mellitus through self-reports and measurement of fasting glucose level in a representative sample of Albanian adults residing in Tirana. Study Design: Cross-sectiona...