Lipid Based Drug Delivery System in Ayurveda - An Overview
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2018, Vol 0, Issue 0
Abstract
Lipids and lipid-based formulations (Snehas) are commonly used in curative as well as preventive aspects in Ayurveda. They are used as food, medicine, vehicle etc. The present review highlights the importance and superiority of unique lipid-based formulations (Sneha kalpanas) from an Ayurvedic and modern perspective. All the important literature from both modern medicine and Ayurveda along with online sources were searched and analysed. In Ayurveda lipids are used alone and/or in processed formulations both internally and externally. It is used to extract lipophilic components and facilitate its delivery to deeper tissues and has the potential to bypass blood brain barrier and placenta that are nonpermeable to hydrophilic components. The lipid-based drug delivery system is superior when compared to aqueous based preparation with respect to absorbability, bioavailability, shelf life, safety, efficacy, and multiplicity in route of administration like oral, parenteral, ocular, intranasal, dermal/ transdermal, transcranial, transplacental and vaginal, abundance in availability. Due to these attributes, Ayurveda classics used ghee, oil and other milk-based formulations in infants, old age, and psychiatric as well as chronic degenerative diseases.
Authors and Affiliations
Krishna Rao. S, Indu. S. , Pradeep Kumar P. P.
Keywords
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