LIPID INDICES IN TYPEII DIABETES MELLITUS AND THEIR ASSOCIATION WITH MACRO AND MICRO VASCULAR COMPLICATIONS
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2013, Vol 2, Issue 1
Abstract
Background: Type II Diabetes Mellitus patients can develop complications over a prolonged period of time. The alterations in lipid indices can be associated with these complications. Aims:To identify changes in lipid metabolism in type 2 DM in context with the glycemic status, its relative impact on the macro & micro vascular events, and the effects of insulin therapy on the lipid indices. Methods and Material: 158 Type II diabetics were selected as cases and 30 subjects without any coincidental illness as controls were selected for the study. Total cholesterol, Triglyceride, HDL-C, Cholesterol/ HDL-C ratio and Atherogenic Index (AI) were estimated and the data was statistically analyzed. Results: Atherogenic index and CHOL/HDL-C levels were significantly higher in diabetics than in controls. Both the indices were also found to be lowered in patients on treatment with insulin. The AI in patients with complications was also significantly higher than those without complications; however CHOL/HDL-C was not significantly different. Thus using the best cutoff values AI can be used as a better indicator for complications than using the ratio of CHOL/HDL-C. Conclusion: AI can be used to indicate the presence of increased cardiovascular risk in patients with type II DM, and as a guide for the aggressive therapeutic approach.
Authors and Affiliations
Imran Ahmed Siddiqui MD| Specialist, Department of Biochemistry ESIC Super Specialty Hospital, Hyderabad Corresponding author email: write2drimran@gmail.com, Laxmikanth B MD| Asst Professor Department of Biochemistry Shri Sathya Sai Medical College & Research Institute, Chennai, Mariya MD| Asst Professor, Department of Anatomy, Shadan Institute of Medical Sciences, Hyderabad, Rama Rao J MD| Professor & Head Department of Biochemistry, Osmania Medical College, Hyderabad
Keywords
Related Articles
- EP ID EP10948
- DOI -
- Views 502
- Downloads 24
Comparison of Mec A Gene in Staphylococcus Aureus Isolated from Children at Time of Admission and Discharge in West of Iran
Staphylococcus aureus (SA) is a species of the genus Staphylococcus that is found everywhere, including in the respiratory tract and on the skin of many adults and children, and that is considered one of the main pathog...
The Effect of Sexual Satisfaction on the Quality of Life on Patients with Cardiovascular Disease
Objective: This study is aimed to assessment the relationship between sexual satisfaction and quality of life(QQL) in patients with cardiovascular disease at the city of Ilam. Background: Heart disease is a leading caus...
The tensity and overtraining on Th1/Th2 balance in wistar male rats
Immune system has role in inflammatory and anti inflammatory function. Base of these activities is produce IL4 and IFNγ. This study is about effects of endurance training with moderate intensity and overtraining on bal...
Effect of the peer supportive program on blood pressure changes in patients affected with hypertension: A randomized controlled trial
Hypertension is the biggest risk factor of death worldwide. The peer supportive program is one of low-cost programs which can be used to enhance patient information in chronic diseases. The aim of this study is to dete...
BACTERIOLOGICAL PROFILE OF WOUND INFECTION IN RURAL HOSPITAL IN R.R DISTRICT
Wound infection is a major problem in hospitals in developing countries. Wound infection causes morbidity and prolonged hospital stay thus the study was undertaken to know the bacteriological profile of wound infection...