Lipid profile in children with Nephrotic syndrome
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2018, Vol 5, Issue 6
Abstract
Background: To study the derangement of serum lipid profile in children 2 to 12 years with nephrotic syndrome. Methods: 50 children 2 to 12 years with nephrotic syndrome were identified. Patients were classified as remission, relapse and newly diagnosed. Lipid Profile was measured. Patients were followed-up after 4 weeks of steroid therapy. Results: Out of all the 50 subjects screened, 25 (50%) subjects had high total cholesterol, 26 (52%) had high triglyceride, 8 (16%) had abnormal HDL cholesterol and 25 (50%) had high LDL cholesterol. After 4 weeks of steroid therapy though there was significant reduction in lipid components. Conclusion: Our study shows that in nephrotic syndrome, there is generalised hyperlipidemia and hypoalbuminemia. Serum cholesterol, triglycerides and LDL cholesterol were deranged in almost all subjects. In cases in relapse after 4 weeks of steroid therapy there is persistent raised total cholesterol, triglycerides and LDL cholesterol, which may predispose to the development of atherosclerosis in near future.
Authors and Affiliations
Sanjay Chavan, Shradha Salunkhe, Anshuman Singh, Sharad Agarkhedkar, Suhas Sodal, Renuka Jadhav
Keywords
Related Articles
- EP ID EP375924
- DOI 10.17511/ijpr.2018.6.03
- Views 161
- Downloads 0
Spectrum of Pediatric Dermatoses in The Pediatric Outpatient Clinic of a Rural Teaching Hospital
Introduction: Skin diseases in the pediatric population are common all over the world including rural and urban areas. There is variation in the pattern and presentation of Dermatoses, with eczemas being the most common...
The role of structured handouts in improving the teaching learning process of final year MBBS students
Introduction: Teaching includes application of various teaching learning methods by a teacher to transfer knowledge and skills to a student. It requires a lot of effort and talents to modify the method more effectively,...
A study on the types of dehydration and serum sodium level in infants and young children at the time of hospital admission with acute diarrhea in rural area of Jharkhand
Objectives: This study was done to know the incidence of different type of dehydration clinically in acute watery diarrhea (mild, moderate and severe) along with serum sodium level (isonatraemic, hyponatraemic, hypernatr...
Study of Osteomyelitis in paediatric patients
Introduction: Osteomyelitis is defined as inflammation of bone. Though the main culprits are bacteria occasionally fungi may also be involved. Prognosis of untreated or delayed treatment onset osteomyelitis is often bad...
Use of NESTROFT as a screening test for the carriers of thalassemia major
Objective: To evaluate the utility of NESTROFT as a screening test for carriers of thalassemia major. Design: prospective study. Settings and participants: Total 121 clinically normal siblings, of thalassemia major patie...