LIPOPROTEIN (a) IN CHRONIC KIDNEY DISEASE
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 10
Abstract
BACKGROUND In Chronic Kidney Disease (CKD) patients, comprehensive care of patients involves not only the management of renal disease, but also the appropriate management of its complications. The study of Lipoprotein (a) levels (LP(a)) in CKD patients becomes important as it expresses the link between Chronic Renal Failure (CRF) and cardiovascular complications. In our study, Lipoprotein(a) is analysed in relation to various criteria in CRF to evaluate the risk group for complications. MATERIALS AND METHODS This study was done for a period of 1 year from April 2017 to March 2018 at Medicine OPD, ward, Nephrology OP and wards, Government KAPV medical college hospital, Trichy. During this period, 50 patients admitted with chronic renal failure of both sexes, irrespective of age were selected and enrolled for the study. RESULTS 37 out of 50 patients had elevated LP(a) levels. Age and sex were not found to be significant factors affecting LP(a). Increased LP(a) levels were seen in patients with severe anaemia, elevated seem creatinine levels, increased diastolic BP and ECG changes. CONCLUSION Elevated serum LP(a) level is very much useful in assessing the risk in CRF as accelerated atherosclerosis, uncontrolled hypertension, coronary artery disease and end stage renal disease.
Authors and Affiliations
Barathiraja P, Raja Mahendran P
Keywords
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- EP ID EP611648
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