Liposome: method of preparation, advantages, evaluation and its application
Journal Title: Journal of Applied Pharmaceutical Research - Year 2015, Vol 3, Issue 3
Abstract
Notable research in drug delivery started in 1950’s with the advent of polyclonal antitumor antibodies developed for targeting. Bangham et. Al. discovered liposomes in early 1960’s. In this review article we are discussing about the liposome, methods of the liposome preparation advantages and their different application of the liposome. Liposomes are artificially prepared vesicles made of lipid bilayer. Liposomes can be filled with drugs, and used to deliver drugs for cancer and other diseases. Liposome is used for the targeted drug delivery system and increase the bioavailability and half life of the any drugs. Liposomes are surfactants, sphingolipids, glycol-lipids, long chain fatty acids and even membrane proteins and drug molecules or it is also called vesicular system. Liposomes have been extensively investigated for drug delivery, drug targeting, controlled release and increased solubility.
Authors and Affiliations
Bhupendra Pradhan, Narendra Kumar, Suman Saha, Amit Roy
Keywords
Related Articles
- EP ID EP215186
- DOI -
- Views 128
- Downloads 0
Liposomes in dermatological diseases
Liposomes are vesicles comprising of spherical phospholipids making them useful for topical applications of drugs. Liposome research has been expanded considerably and nowadays, it is possible to construct a wide range o...
Formulation and evaluation of enteric coated microcapsules of diclofenac sodium for modified release by combination of wet granulation and thermal change method
The purpose of the present work was to develop optimized novel enteric microcapsules containing diclofenac sodium, a non steroidal anti inflammatory drug (NSAID) used for rheumatoid arthritis, for improved delivery and t...
Bioelectrode based chitosan-nano copper oxide for application to lipase biosensor
Chitosan (Chit)-nanocrystalline CuO composite prepared from Chitosan and CuO nanoparticles by a spin coating method. CuO nanoparticles (45 nm) synthesized by Sol-gel citrate method and characterized by X-Ray diffraction...
Design and in vitro evaluation of mouth dissolving tablets olanzapine
The purpose of this research was to design and evaluate the olanzapine fast dissolving tablets. The variable formulation of Olanzapine having challenging methodology. Olanzapine practically insoluble in water so used di...
Stilbenes: chemistry and pharmacological properties
Medicinal plants are the most important source of life saving drugs for the majority of the Worlds’ population. The compounds which synthesized in the plant from the secondary metabolisms are called secondary metabolites...