Littoral cell angioma mimicking metastatic tumors
Journal Title: Current Issues in Pharmacy and Medical Sciences - Year 2015, Vol 28, Issue 4
Abstract
Littoral cell angioma is a rare primary, vascular tumor thought to originate from the endothelial cells lining the sinuses of the splenic red pulp (the “littoral cells”). It is a benign, usually asymptomatic lesion diagnosed incidentally. Ultrasound and tomography appearance is not characteristic and histopathological examination is required. This work provides a case-study of littoral cell angioma which was seen in a 55-year-old female who complained of non-specific upper abdominal pain. Computed tomography revealed multiple hypo-attenuated splenic lesions suggestive for metastasis. A splenectomy was performed and routine microscopic examination supported by immunohistochemistry reactions with CD68, CD34 and CD31 showed littoral cell angioma.
Authors and Affiliations
Justyna Szumiło, Anna Ostrowska, Małgorzata Zdunek, Slawomir Rudzki, Tomasz Chrościcki, Elzbieta Czekajska-Chehab, Franciszek Burdan
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