Liver Fibrosis-Novel Therapy Perspective
Journal Title: Open Access Journal of Pharmaceutical Research - Year 2017, Vol 1, Issue 7
Abstract
Liver fibrosis is highly prevalent in United States. No therapy has been successful to cure it so far. The current approaches in treatment are to prevent its causative etiology such as viral infection, alcohol abuse etc. or liver transplantation. Much progress has been made to understand the mechanisms for development of myofibroblasts in developing fibro genesis, inflammation and cell death. This review summarizes some of the key aspects of liver fibrosis and some novel therapies that have a potential to become a cure.
Authors and Affiliations
Panakanti R*
Determination of Hydrochlorothiazide in Plasma by High Performance Liquid Chromatography (HPLC)
Retention times for hydrochlorothiazide (HCTZ) and chlorothiazide (CTZ, internal standard) are highly temperature- (20°-26°) as well as pH-dependent (3.5-6.3). Separation of both drugs is maximized in the pH range 6.3 to...
Virtual Screening and Validation of Potential Lead Compound from the Malaria Box against Plasmodium Falciparum S7 and S19 Proteins
Molecular docking is a computer based tool used in drug design, where predominant binding modes of a ligand with known three dimensional protein structures are predicted. This study addresses the possible ways of coming...
Phytochemical Screening of Some Spices Used as Condiment in Kano, North western Nigeria
Spices have been added to foods since ancient times, not only as flavouring agent, but also as food preservatives and folk medicines. The study was aimed to screened for qualitative and quantitative bioactive constituent...
Importance of Nanotechnology in Drug Delivery
The branch of technology that deals with dimensions and tolerances of 1-100 nanometres, especially the manipulation of matter on an atomic, molecular and supramolecular scale, is known as ‘Nanotechnology’.
Assessment of Pharmacist Awareness Knowledge and Attitude of Fluranizine in Rafha Saudi Arabia
Objective: This research was aimed to provide a platform for conducting assessment of knowledge and attitude of the pharmacist in Rafha city, Saudi Arabia about Flunarizine. Methods: A cross-sectional research design in...