Liver overload in Brazilian triathletes after half-ironman competition is related muscle fatigue
Journal Title: Annals of Hepatology - Year 2008, Vol 7, Issue 3
Abstract
Triathlon competition is dependent on the athletes’ ability to perform each discipline at optimal time, without excessive fatigue influencing the next one. Objectives: Determine the effects of a long distance triathlon on biochemistry parameters related to liver function. Design and methods: Blood samples from six athletes were collected before (T = 0) and immediately after the triathlon competition (T = 1). AST, ALT and alkaline phosphatase (ALP) values were assessed. Results: Significant changes after triathlon competition were found for AST and ALP and no significant changes were found for ALT over time. Conclusions: A series of metabolically alterations, mainly related to energy production and also to muscle and skeletal adaptations occurs during and after strenuous exercise. The altered status of those metabolical changes cannot directly reflect the intensity of any possible muscular or hepatic damage or overload and elevated AST/ALT ratio is better associated to skeletal muscle lesion during competition.
Authors and Affiliations
Marcos Bürger-Mendonça, Monica Bielavsky, Fernanda Barbosa
Keywords
Related Articles
- EP ID EP77796
- DOI -
- Views 131
- Downloads 0
Hepatoprotective Effect of Curcumin on Hepatocellular Carcinoma Through Autophagic and Apoptic Pathways
Background and rationale. Microtubule-associated protein light chain 3-II (LC3-II), and Sequestosome-1 (SQSTM1) are proteins that can be used as markers for autophagic pathway. Bcl-2 protein is reported to be inversely c...
Giant cavernous hemangiomata of the liver: Watchful waiting, resection or transplantation?
Usefulness of liver biopsy in chronic hepatitis C
Major requirements for performance of liver biopsy (LB) are the benefits for the patient and the impossibility of having the same information by less invasive procedures. In the last two decades physicians have faced the...
Notch signal protects non-parenchymal cells from ischemia/reperfusion injury in vitro by repressing ROS
Background. We have previously reported that Notch signaling pathway protects hepatocytes from ischemia/ reperfusion (I/R) injury by repressing reactive oxygen species (ROS) production. However, apart from hepatocytes, n...
Thrombosis of the Portal Venous System in Cirrhotic vs. Non-Cirrhotic Patients
Introduction and aim. Thrombosis is a vascular disorder of the liver often associated with significant morbidity and mortality. Cirrhosis is a predisposing factor for portal venous system thrombosis. The aim of this stud...