Long QT syndrome type 2 – can alarm clock really kill? (RCD code: V-1A.2)
Journal Title: Journal of Rare Cardiovascular Diseases - Year 2014, Vol 1, Issue 7
Abstract
This paper’s aim was to critically analyze existing research supporting statement found in many review articles that auditory stimuli may specifically and exclusively trigger cardiac events in patients with type 2 of congenital long QT syndrome (LQTS2). By the use of thorough systematic literature search relevant papers were gathered and analyzed. As a result, 8 publications were included in this analysis: 5 case-series studies, 2 single case reports and 1 expert opinion. 5 of the studies proved that auditory stimuli often precede cardiac events in patients with many types of congenital long QT syndrome (LQTS). None of the included studies concerned auditory stimulus as an exclusive trigger of cardiac events in LQTS2 patients (it was most often combined with exercise and/or sleep, or performed on groups with small part of LQTS2 patients). There is lack of strong evidence that auditory stimuli specifically and exclusively trigger cardiac events in patients with LQTS2. However, high occurrence of cardiac events shortly after being awoken from sleep by auditory stimuli and nocturnal deaths in families of patients with LQTS2 may provide indirect support. Due to high risk associated with auditory stimuli for patients with all types of LQTS it is still advisable for them to remove loud and noisy equipment from their close environment. JRCD 2014; 1 (7): 4–6
Authors and Affiliations
Marek Czajkowski
Keywords
Related Articles
- EP ID EP245420
- DOI 10.20418/jrcd.vol1no7.112
- Views 116
- Downloads 0
Genetics and genetic testing in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a rare disease with a high mortality and complex pathomechanism. Recent studies suggest an important role of genetic factors in the development of PAH. It was shown that patients...
Myocardial infarction in Fabry disease – misfortune or companion? Case report and review of the literature
We discuss a 56‑year‑old man with Fabry disease (FD), a genetic X‑linked glycolipid storage disorder. The patient presented at the Emergency Room in a local hospital due to tachycardia‑associated chest pain, which had oc...
The association between aortic stenosis and intestinal angiodysplasia – the Heyde’s Syndrome (RCD code: VIII-1)
Heyde’s syndrome is defined as a combination of gastrointestinal bleeding from a gastrointestinal angiodysplasia in patients with aortic stenosis. An acquired von Willebrand factor deficiency secondary to aortic stenosis...
Metastatic tumor of the left atrium (RCD code: VI‑2O)
We present a case report concerning a 59-year-old patient diagnosed with intracardiac tumor two years after removal of soft tissue sarcoma of the right lower extremity.
Cavernous hemangioma of the heart in a 37‑year‑old male visualized by multislice computed tomography (MSCT) (RCD code: VI‑1B.4)
A 37‑year‑old male with a 6‑month history of atypical nonexertional chest pain and markedly limited exercise capacity was referred for evaluation to our department. He had no previous medical history. There were no patho...