Longitudinal Assessment of FEV1 Change Following Autologous Cellular Therapy
Journal Title: Journal of Regenerative Medicine & Biology Research - Year 2021, Vol 1, Issue 1
Abstract
Objective: Current pharmacologic management of Chronic Obstructive Pulmonary Disease (COPD) is aimed at improving symptoms and preventing exacerbations, yet none can alter the natural progression of lung function decline typical of the disease. Autologous-derived PRPPC may prevent lung function decline and improve quality of life. Methods: 281 patients with COPD underwent autologous cellular therapy with PRP-PC. Baseline lung function and quality of life data were collected and re-assessed after 3 months and after at least 12 months and compared to baseline. Results: Participants undergoing autologous cellular therapy with PRP-PC had a and clinically significant increase in lung function after both 3 months and after at least one year with along with a significant improvement in subjective quality of life from baseline. Compared with findings in the literature that FEV1 typically declines over time, participants in this study had a significant increase in lung function on average. Conclusion: Innovative treatments such as autologous cellular therapy can be a safe, effective option for preventing lung function decline over time. These therapies should be an option for patients where pharmacologic management has failed, or as an adjunct treatment.
Authors and Affiliations
Melissa M Rubio
Keywords
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- EP ID EP698851
- DOI http://dx.doi.org/10.46889/JRMBR.2021.2101
- Views 63
- Downloads 0
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