Low and Zero Prevalence Rates of Anti-measles Virus Immunoglobulin G in Mothers and Their Infants Respectively in Health Centers in Osogbo, Nigeria
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2014, Vol 4, Issue 32
Abstract
Aim: We undertook this study to determine the susceptibility of mother-infant pair participants to measles virus infection in two health centers in Osogbo, Osun State, Nigeria. Study Design: This is a descriptive, cross-sectional hospital-based study. Place and Duration of the Study: The study was carried out in Osogbo, southwestern, Nigeria between November, 2012 and February, 2013. Methodology: With ethical approval and participants’ consents, 83 mothers and their 84 infants were consecutively recruited; blood samples were aseptically collected from them by thumb puncture onto Whatman filter paper. The papers were appropriately labeled; air-dried and kept in brown envelopes which we kept in clean polythene bags and stored at 4ºC until assayed. Freshly prepared PBS was used to elute serum from 5 to 6 punched-out disks from each Whatman filter paper. The supernatant from the spun eluate of each sample was assayed for anti-measles virus IgG using ELISA. Results: Overall, 2.41% and zero percent seroprevalence rates were recorded from the nursing mothers and their infants respectively. Conclusion: We concluded that the seropositivity of anti-measles virus IgG antibody in the nursing mothers from the two health facilities was very low, and that all the infants and most (97.59%) of the nursing mothers were apparently susceptible to measles virus infection.
Authors and Affiliations
Oluwatoyin Adebusola Adegboye, Adetayo Abosede Adegboye, Moses Olubusuyi Adewumi, Waidi Folorunso Sule
Keywords
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- EP ID EP349017
- DOI 10.9734/BJMMR/2014/9738
- Views 68
- Downloads 0
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