Low Prevalence of Plasmodium vivax - Plasmodium falciparum Mixed - Infection in Patients from Central and Eastern Part of Sudan: Implication for Case Management in Sudan
Journal Title: International Journal of TROPICAL DISEASE & Health - Year 2014, Vol 4, Issue 8
Abstract
Accurate diagnosis of malaria parasite species is crucial for rational treatment that is a key success for a malaria control and elimination programmes. The main objective of this investigation was to correct species identification and re-assessment of diagnosis method in central and eastern part of Sudan. The blood samples were collected from 71 febrile cases infected with P. vivax in Eastern and Central Sudan, diagnosed by light microscopy and also by nested-PCR assay, using 18S small sub-unit ribosomal RNA (ssrRNA) gene. The nested-PCR were detect 92.9% (66/71) and 2.8% (2/71) P. vivax and P. falciparum mono-infection, respectively. Based on microscopy method, the level of mixed - Infection was zero; however, nested-PCR assay detected 4.2% (3/71) mixed infections in collected samples. In detecting P. vivax infection, microscopy had high sensitivity (97%) and specificity (50%). In conclusion, the present data point to the need of improving microscopy diagnosis method in malaria endemic region and also suggest that although molecular techniques are not practical for diagnosis of P. vivax and P. falciparum mixed infections in any areas; these could be used to collect epidemiological facts for control and elimination of the disease in Sudan.
Authors and Affiliations
Albadawi A. Talha, Sakineh Pirahmadi, Elgaily M. Elgaily, Sedigheh Zakeri, Bakri Y. M. Nour
Keywords
Related Articles
- EP ID EP343403
- DOI 10.9734/IJTDH/2014/10916
- Views 66
- Downloads 0
A Five Year Retrospective Study of Vascular Tumours at Federal Medical Center Makurdi and Benue State University Teaching Hospital
Aim: To determine the prevalence of vascular tumours, and their morphology at Federal Medical Centre and Benue State University Teaching Hospital Makurdi. Study Design: Retrospective study of vascular tumours at the two...
Transporting Snake Bite Victims to Appropriate Health Facility within Golden Hour through Toll Free Emergency Ambulance Service in India, Save Lives
Background: Snakebite is a neglected public health issue in India. The big four venomous snakes are Cobra, Krait, Russell’s viper and Saw scaled Viper. Estimates of annual snakebite mortality in India are upto 50,000 dea...
Spatial and Temporal Variations of Maternal Deaths in Borno State of Nigeria: An Institutional Based Study
Aim: The aim of the study is to describe and explain the spatial and temporal variations of maternal mortality between different regions of Borno State, Nigeria. Method: This is a retrospective patient record study, whi...
Ergonomics Workstation Assessment of Musculoskeletal Disorders in University of Port Harcourt
This study examines the experiences of musculoskeletal discomfort among staff and students of the University of Port Harcourt as it relates to their workstations. Questionnaires were designed to extract information from...
Socio – economic Factors Influencing Utilization of Healthcare Services in Sokoto, North-Western Nigeria
The objective of equity in health care system is “equal access for equal needs” and there should be no barriers to healthcare utilization. The objective of the study was to assess the socio – economic factors influencing...