<strong>Acute respiratory distress syndrome (ARDS) complicating influenza <em>A/H1N1v</em> infection - a clinical approach.</strong>
Journal Title: Annals of Agricultural and Environmental Medicine - Year 2013, Vol 20, Issue 4
Abstract
ARDS is defined as an acute inflammatory syndrome characterized with bilateral parenchymal lung infiltrates on chest radiograph and PaO[sub]2[/sub]/FiO[sub]2[/sub] ratio&amp;lt;200 resulting from causes other than acute left ventricular dysfunction. Inflammatory lung lesions may be induced by different disorders, with sepsis being the leading cause of ARDS. Other causes include infectious pneumonia, aspiration of gastric contents, drugs, severe trauma, fat embolism, surface burn, massive blood transfusion. Influenza A/H1N1 infection seems to be responsible for the development of extremely severe type of ARDS with poor response to routine treatment. Despite great progress in the management of ARDS with novel agents and sophisticated techniques, including antimicrobial drugs, extracorporeal membrane oxygenation, prostaglandins, nitric oxide, prostacyclin, exogenous surfactant administration and activated protein C, supportive treatment based mostly on advanced mechanical ventilation in the intensive care units seems to be the most important for the prognosis.
Authors and Affiliations
Agnieszka Witczak, Andrzej Prystupa, Ewa Kurys-Denis, Michał Borys, Mirosław Czuczwar, Marcin Niemcewicz, Janusz Kocik, Anna Michalak, Aldona Pietrzak, Grażyna Chodorowska, Witold Krupski, Jerzy Mosiewicz, Krzysztof Tomasiewicz
Keywords
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