Lycopene and Cardiovascular Diseases: A Review of the Literature
Journal Title: International Journal of Research and Review - Year 2017, Vol 4, Issue 1
Abstract
Cardiovascular diseases (CVD) are the leading causes of human disability and premature death throughout the world. Diet has a direct link with the development of CVD and so dietary change is the current approach for the prevention of CVD that is to increase the consumption of fruits and vegetables as good sources of several antioxidant phytochemicals, e.g. carotenoids. Lycopene, the most abundant carotenoid in tomatoes and tomato products has gained profuse attention in recent years for its health beneficial role, especially those related to its effects as an antioxidant and its protective role against CVD. So, the objective of this review is to assess the effect of lycopene in CVD and/or CVD risk factors studying epidemiological, clinical and biochemical data. Among twenty-three epidemiological studies investigating the association between lycopene and CVD, eight studies have found no association whereas other fifteen studies have indicated an inverse association. In case of in vivo and in vitro cell culture studies, the results are still inconsistent; some provide evidence in favor of lycopeneor tomato supplementation to reduce the prognosis of CVD and others do not support the cardio protective role of lycopene. In contrast, animal studies have provided a more vivid result, most have showna favorable effect of lycopene towards preventing CVD risk. In summary, ignoring the controversies, there lies a demand for more specific and focused research on lycopene, particularly to have a better and comprehensive understanding of lycopene’s role in human health and disease for a better-quality life.
Authors and Affiliations
Towhid Hasan
Keywords
Related Articles
- EP ID EP366801
- DOI -
- Views 129
- Downloads 0
Learning Motivation of Students During the Implementation of Lecturing Based in Silico Approach
The silico-based learning is one of the new curriculum programs for prospective teachers at UN PGRI Kediri. Because of motivation plays an important role, this study aims to reveal the dimension of students' learning mot...
Structural Performance of Cold Formed Steel Angle
The paper describes the results from a finite element investigation into the load capacity tension members of single angle sections of 2, 3 mm 4 and double angles sections of 2mm under plain (without Lipped) and with Lip...
Contribution of Agricultural Loans Accessibility to Performance of Small Holder Sugar Cane Farmers in Kakamega County, Kenya
Agricultural growth is important for alleviation of poverty and stimulation of economic growth and development. The main objective of this study was to investigate the contribution of agricultural loans on performance of...
Yield Stability and Agronomic Performance of Rain Fed Upland Rice Genotypes by Using GGE Bi-Plot and AMMI in North West Ethiopia
The study was conducted at Fogera, Pawe, Assosa, Gondar and Mai-tsebri in Ethiopia during 2016-2017 with the objective of identifying high yielding, major disease resistance and stable rice varieties for rain fed upland...
Human Resource Quality in East Java, Malang Regency Administrative Staff Working Performance Enhancement
This research purpose is to test the influence of human resource quality, commitment, and motivation towards administrative staff performance in Malang Regency Regional Secretariat, either simultaneously or partially. Th...