Lymph Node Dissection in Interval Debulking Surgery: Two Years Analysis
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 12
Abstract
Background and Objectives: ovarian cancer comprise 4% of all women cancer and 34% amongst gynaecological tract cancer. Lymphatic dissemination to the pelvic and para-aortic lymph node seen in usually advanced stage disease. Retroperitoneal lymph node involvement occur in approximately 50% to 80% of women with advanced ovarian cancer. The role of routine lymph node dissection is still not clear in interval debulking surgery. Materials and Methods: all ovarian histologically proven adenocarcinoma cases receiving neoadjuvant chemotherapy and undergoing debulking surgery with or without routine lymphadenectomy operated during the period 2013-14 were included in the study and divided into control and cases arm. Outcome measurement were done in relation to progression-free survival (PFS) to detection of progression of disease or death with number of hospital stay peri-operative and postoperative complication. Results: Lymph node dissecting group of patients showed longer intraoperative period with significant amount of blood loss with longer hospital stay without any benefit over overall and progression free survival. Conclusion: a routine pelvic lymphadenectomy for stage III and IV ovarian cancer during interval debulking has no advantage over recurrence and progression or overall survival and is associated with higher morbidity
Authors and Affiliations
Dimpy Begum Fellow
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