LYMPHOCYTE SUBSETS IN BRONCHOALVEOLAR LAVAGE FLUID OF CHILDREN WITH LUNG INFILTRATES
Journal Title: Acta Facultatis Medicae Naissensis - Year 2012, Vol 29, Issue 3
Abstract
The analysis of the subpopulation of lymphocytes - CD4+, CD8+ lymphocytes in bronchoalveolar lavage (BAL) of paediatric patients can provide useful information related the lung parenchyma. The aim of the paper was to analyze the results of bronchoscopy of patients presenting with persistent lung infiltrates and to find out of the diagnostic yield and complication rate of this procedure. The study is a retrospective one. The data related to paediatric findings and BAL results of the bronchoscopies were retrieved from the hospital records. BAL was performed in tracheobronchial airways (middle lobe) by bronchoscope and sent to analysis of CD4+, CD8+ lymphocytes. Bronchoscopy was performed under general anesthesia (sedation, propofol, midazolam, morphium). The records of seven patients were analyzed. All patients presented with persistent lung infiltrate (atelectasis and pneumonia). 71% of the patients with lung infiltrates in our study were below the age of 5. Our study results showed that CD4+, CD8+ lymphocytes in BAL in the studied group showed a small percentage of CD8+ lymphocytes as an immune response in 8-10% of patients, while the cellular response of CD4 +lymphocytes in the sample itself was present up to 14% in the entire group of the diseased children. There was no serious desaturation during bronchoscopy. Bronchoscopy with BAL findings of lymphocyte populations is important in the early identification of inflammation and it helps in therapeutic strategies and monitoring of inflammatory response to the given therapy.
Authors and Affiliations
Amina Selimović, Senka Mesihović Dinarević, Tatjana Pejčić, Ermina Mujičić, Aida Hasanović, Siniša Ristić, Nataša Banjac, Željko Pavlović
Keywords
Related Articles
- EP ID EP110221
- DOI 10.2478/v10283-012-0019-1
- Views 121
- Downloads 0
MARGINALNA PUKOTINA I OŠTEĆENJE GLEĐI OKO ADHEZIVNIH RESTAURACIJA ZUBA (in vitro SEM ispitivanje)
Postoje tri adhezivna restaurativna sistema: nagrizanje uz ispiranje, “etch and rinse”, samo nagrizanje “self etch” i glas jonomer sistem. Marginalna pukotina i oštećenje marginalne gleđi oko kompozitnih i glas jonomer r...
QALY - MERA ZA ANALIZU ODNOSA TROŠKOVA I KORISTI ZDRAVSTVENIH INTERVENCIJA
Za potrebe ekonomske evaluacije, u okviru zdravstvene ekonomike, koristi se nekoliko analitičkih tehnika, koje su dizajnirane za potrebe komparacije dve ili više zdravstvenih intervencija u pogledu troškova i rezultata....
FUNKCIONALNI ISHOD I KVALITET ŽIVOTA NAKON RESTORATIVNE PROKTOKOLEKTOMIJE I ANASTOMOZE ILEALNOG PAUČA SA ANUSOM KOD STARIJE POPULACIJE
Restorativna proktokolektomija sa anastomozom ilealnog pauča sa anusom je hirurška metoda izbora koja se primenjuje kod bolesnika sa medicinski refraktornim ulcerativnim kolitisom, ulcerativnim kolitisom sa displazijom i...
EPIDEMIOLOGICAL CHARACTERISTICS OF CARRIERS OF ANTIBODY AGAINST HEPATITIS C VIRUS IN THE POPULATION OF NIŠAVA DISTRICT
The aim of the paper was to determine the disease trends and characteristics of anti-HCV antibody carrier status for the purpose of better prevention and disease control. The materials used were annual reports, reports o...
Rehabilitation of a Female Patient after Corrective Surgery for Tetralogy of Fallot
Herein we present a 25-year-old female patient with tetralogy of Fallot (TOF). This congenital heart defect is not very common, but it is the most common one among cyanotic heart defects. Treatment of the patients with...