Lymphocytic Thyroiditis with Associated Lesions in Coastal Areas of Alappuzha - A 2-Year Study
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 8
Abstract
Introduction: The prevalence of goiter and thyroid disorders is influenced by low iodide intake as seen in areas far remote from seacoast. Around 400 cases of goiter were reported in MCH, Alappuzha, every year. The present study was done to know the increase in lymphocytic thyroiditis (LT) cases and associated lesions like coexistent papillary carcinoma in such iodine sufficient coastal areas. Aim: This study aims to assess the frequency of LT and study the associated lesions. Methods: The study was done in all thyroidectomy specimens during a period of 2 years. Clinical details were collected with a standard pro forma. Specimens were fixed with 10% formalin and histological sections were stained with hematoxylin and eosin. Grading of LT was done using histologic criteria of Williams and Doniach. Results: Of the total biopsies received in our Histopathology Department (TDMC, Alappuzha) in a 2-year period (2005 and 2006), 5.19% were thyroid lesions and among the total 683 thyroidectomy specimens, LT constituted 208 cases (30.45%). In our study, incidence of LT in females is 18.63% compared to males 0.874% and the age peaked around 3rd–4th decade The major proportion (96.4%) belongs to the very severe (Grade 4) category. In our study, out of the 58 carcinomas, 51 were papillary thyroid carcinomas and 26 of them had coexistent lymphocytic thyroiditis. Conclusion: The increased frequency of LT in coastal areas of Alappuzha may be is due to excess intake of iodide. Prognostic influence of papillary carcinoma in coexistent lesions has to be studied further. Iodine supplementation should be maintained at a safe level to prevent autoimmune diseases.
Authors and Affiliations
K Jayasree, T S Sudhiraj, M B Jayaraman
Keywords
Related Articles
- EP ID EP483010
- DOI -
- Views 142
- Downloads 0
Basics of Management of Medical Emergencies in Dental Offi ce and Emergency Drug Kit
Medical emergencies are rare medical events that may occur unexpectedly in the dental offi ce during dental treatment. If encountered those events require immediate diagnosis and management to avoid potential consequence...
Correction of Transverse Discrepancy Using Rapid Maxillary Expansion with Hyrax Appliance: A Case Report
A 14 years young patient presented for the correction of a malocclusion that included a transverse maxillary deficiency. The patient had required to expand his upper jaw to correct his malocclusion. Recent evidence indic...
Mandibular Ramus: An Indicator for Gender Determination - A Digital Radiographic Study
Aims and Objectives: The objectives of this study were as follows: (1) To measure, compare, and evaluate the various measurements of mandibular ramus as observed on orthopantomographs and (2) to assess the usefulness of...
Clinical Study of Foreign Body in Aerodigestive Tract
Aim: The present study of foreign bodies in aerodigestive tract was undertaken to study the various parameters basis of history, examination, and investigations. Materials and Methods: A total of 72 cases of foreign bodi...
Clinical Study of Lipid Profi le Pattern in Acute Coronary Syndromes
Introduction: Acute coronary syndrome is one of the leading cause of morbidity and mortality in the world today. There has been constant effort on the part of medical researchers to analyze this problem and search for fa...