Magnesium Administration For COPD Exacerbation: A Systematic Review and Meta-analysis
Journal Title: The Journal of Medicine, Law & Public Health (JMLPH) - Year 2021, Vol 1, Issue 2
Abstract
BACKGROUND The role of magnesium in patients with acute chronic obstructive pulmonary disease (COPD) exacerbation remains to be determined. AIM We aim to explore the effect of magnesium on COPD exacerbation, as well as its impact on pulmonary function tests and on hospital admissions for acute exacerbation in the emergency department. METHODS This is a systematic review and meta-analysis that included a search of the keywords "magnesium" and "COPD" on PubMed, Google Scholar, Cochrane databases, and Gray literature (ClinicalTrials.gov and World Health Organization International Clinical Trials Registry Platform) from 1963 to May 2021. RESULTS The use of IV magnesium reduced the risk ratio for admission RR= 0.85 (95% CI 0.62 to 1.17). The combined risk ratio for admission increased to 0.95 when we added nebulised magnesium sulphate (95% CI 0.85 to 1.07), p>0.05. The mean score for improvement after IV magnesium was higher (M=16.75, SD=5.11) than the mean score before its administration (M=8.74, SD=8.85), t(4)=-2.57, p=0.031. Thus, the use of IV magnesium sulphate results in a 91.64% improvement in the pulmonary function test. CONCLUSION IV magnesium sulphate improves the pulmonary function test of patients with acute COPD exacerbation in the ED, and possibly reduces the admission rate.
Authors and Affiliations
Hala Alzaid, Fay Aldossari, Sharafaldeen Bin Nafisah
Role of Venous Blood Gase (VBG) Analysis in Patient Triage in the Adult Emergency Department
Background: In emergency and critical care settings, can a venous blood gas analysis improve clinical decision-making and patient outcomes? Methods: This is a cross-sectional study, conducted between January and...
The Risk of Post-Traumatic Stress Disorder (PTSD) among Frontline Healthcare Workers in Saudi Arabia during the COVID-19 Pandemic: A Cross-sectional Study
Background: Frontline healthcare workers (HCWs) are at risk of developing post-traumatic stress disorder (PTSD) due to the nature of their work and, due to the additional stress and mental fatigue brought on by the COVID...
A Review of Advance Directives
The use of an advance directive, when drafted in accordance with the MCA, allows a person the right to refuse specified treatment at a later stage of their life, should they become incapacitated. This means that they, ra...
Virtual Versus In-Personal Teaching of Infection Control Essentials: A Quasi-Experimental Nonequivalent Groups Design
BACKGROUND In setting of the current COVID-19 pandemic, it is crucial to endorse infection control competencies. However, whether virtual training is equivalent to in-person teaching to develop such competencies requires...
Enhancing Dispatch Systems for Out-of-Hospital Cardiac Arrest: A Proposal for Improved Survival Outcomes
Early and effective cardiopulmonary resuscitation (CPR) is critical for survival and neurological recovery in cases of out-of-hospital cardiac arrest (OHCA). This commentary proposes a novel approach involving the use of...