Magnetic Resonance Imaging Evaluation of Hippocampus with T2 Relaxation Time
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 1
Abstract
Objective: The objective of the study is to acquire the data of hippocampal volumes (HV) and T2 relaxation times, to assess and compare qualitative and quantitative evaluations in determining hippocampi in patients with divergent durations of intractable epilepsy, and to initiate an imaging protocol based on the production of these techniques. The foremost magnetic resonance imaging (MRI) features of hippocampal sclerosis (HS) are volume loss and increased T2 weighted signal intensity. Minor abnormalities may be missed without careful quantitation. In this study, hippocampal T2 was calculated along the entire length of the hippocampus on adjacent slices and used, with quantitative measures of HV and distribution of atrophy, to better describe the range of HS. Methods: A total of 50 patients with temporal lobe epilepsy (TLE), 20 patients with extratemporal localization-related epilepsy and extratemporal lesions, and 30 control subjects were studied using MRI T2 relaxometry and volumetry. Results: In controls and patients, HT2 was higher in the anterior than the posterior hippocampus. Patients with bilateral hippocampal involvement had an earlier onset of epilepsy than patients with unilateral HS. Conclusions: Calculation of regional abnormalities of hippocampal T2 relaxation along the length of the hippocampus gives the advance improvement to the MRI assessment of the hippocampi in patients with TLE and is corresponding to the volumetric and morphological data.
Authors and Affiliations
Vasudave Nataraja
Keywords
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