MAGNITUDE OF AUTONOMIC NEUROPATHY IN TYPE 2 DIABETES MELLITUS PATIENTS OF MORE THAN 5 YEARS DURATION IN A TERTIARY CARE HOSPITAL OF ODISHA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 12
Abstract
BACKGROUND Autonomic neuropathy in type 2 diabetes mellitus patient is a serious and common complication of diabetes that is most often ignored by most of the clinicians. Diabetic autonomic neuropathy is among the least recognized and least understood complication of diabetes, despite its significant negative impact on survival and quality of life. It can involve multiple systems including cardiovascular, gastrointestinal, genitourinary, sudomotor, metabolic systems, and papillary dysfunctions. MATERIALS AND METHODS 88 patients of type 2 diabetes mellitus of more than 5 years duration with the age more than 30 years of either sex were studied which as a descriptive study conducted in the department of general medicine of SCB medical college. Cardiovascular autonomic neuropathy was evaluated with regard to 5 parameters (heart rate, orthostatic hypotension, hand gripping test, QTc interval in ECG, exercise intolerance by treadmill test). For gastrointestinal autonomic neuropathy, genitourinary autonomic neuropathy, hypoglycaemic unawareness, pupillary abnormality, sweating disturbances, only signs and symptoms will be noted as most part of the evaluation would be done only in research laboratory, which requires specialized equipment. For erectile dysfunction, patients will be asked to fill questionnaires according to IIEF-5. (31,32). Prevalence of autonomic neuropathy was categorised into mild, moderate and severe among different age group of people, in both sexes based on duration of diabetes, body mass index (BMI) and was expressed as percentages. RESULTS Out of total 88 cases, 15 patients (17.0%) didn’t have autonomic neuropathy, 22 patients (24.0%) had mild autonomic neuropathy, 33 patients (37.5%) had moderate autonomic neuropathy, 18 patients (20.3%) had severe autonomic neuropathy. Duration of diabetes and body mass index were risk factor whereas age and sex were not a risk factor for autonomic neuropathy in diabetes mellitus patients. CONCLUSION Overall prevalence of diabetic autonomic neuropathy in our study is 81.8%, among them mild is 24%, moderate is 37.5%, and severe is 20.3%. So, it should be evaluated in every diabetes patient of more than 5 years duration. Duration of diabetes and BMI are risk factors for autonomic neuropathy in diabetes mellitus patients
Authors and Affiliations
Meghanad Meher, Jayanta Kumar Panda, Siddhartha Dash, Lavina Patnaik
Keywords
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- EP ID EP555630
- DOI 10.14260/jemds/2019/192
- Views 64
- Downloads 0
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