Makrofagi - cichy przeciwnik w młodzieńczym idiopatycznym zapaleniu stawów
Journal Title: Advances in Hygiene and Experimental Medicine - Year 2016, Vol 70, Issue
Abstract
Authors and Affiliations
Joanna Świdrowska-Jaros, Krzysztof Orczyk, Elżbieta Smolewska
The role of the Fanconi anemia pathway in DNA repair and maintenance of genome stability
The Fanconi anemia (FA) pathway is one of the DNA repair systems involved in removal of DNA crosslinks. Proteins which belong to this pathway are crucial to the protection of genetic information, whereas disturbances in...
Mechanisms of programmed cell death of effector T lymphocytes
T cell adequate function is critical for defense against pathogens. Transient disruption of T cell homeostasis occurs when primarily naive cells undergo antigen-driven expansion and acquire effector functions. Effector T...
Ceruloplazmina, hefajstyna i cyklopen: trzy multimiedziowe oksydazy uczestniczące w metabolizmie żelaza u człowieka
Oksydazy multimiedziowe to grupa białek o aktywności enzymatycznej, które są zdolne do utleniania substratów w reakcjach, którym towarzyszy czteroelektronowa redukcja tlenu cząsteczkowego do dwóch cząsteczek wody. Udowod...
The other face of MUC1 protein in cancer progression – the role of MUC1-C subunit
MUC1 is high-molecular-weight glycoprotein which is widely expressed on epithelial cell layers of various organs and is aberrantly overexpressed in most human carcinomas such as breast, ovarian or colon cancer. MUC1 cont...
The role of Toll-like receptors in the pathogenesis of allergic diseases – where is the truth?
Toll-like receptors (TLRs) are pattern recognition receptors crucial for the innate and adaptive immune response to pathogen-associated molecular patterns (PAMPs). TLR stimulation via microbial products activates antigen...