Malherbe's calcifying epithelioma (pilomatrixoma) in childhood; Reviewed 105 cases observed over 10 years.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 1
Abstract
Pilomatrixoma is an uncommon benign skin tumour that is usually seen in children and adolescents, and can be treated with surgical excision. The aim of this study was to evaluate the clinical characteristics of these lesions that can cause difficulties in diagnosis, and to discuss the differential diagnosis, histopathological characteristics and follow-up in the context of the literature. A retrospective examination was made of 105 cases which were treated with excisional biopsy for a subcutaneous mass, which was then pathologically diagnosed as pilomatrixoma between 2008 and 2017. The cases were evaluated with respect to age, gender, lesion diameter, location, recurrence, and histopathological characteristics of the lesions. A total of 113 lesions were detected in 105 patients comprising 75 females and 30 males. The mean age at diagnosis was 8.9 years. In 3 patients, 2 lesions were determined in separate locations on presentation. The lesions were localized on the head and neck in 48 cases, on the upper extremities in 38, on the trunk in 18, and on the lower extremities in 9. The diameter of the lesions ranged from 0.3 to 3 cm. Within the study period, recurrence developed in the same location after 1 year in 1 patient, and a separate second lesion developed after mean 3.7 years in 4 cases. In the present study, a realistic comprehensive picture of pilomatrixoma in our central hospital has been provided. It’s manifestation is diverse and easily misdiagnosed. Early complete excision is recommended for hard or firm nodules on head, neck and upper extremity.
Authors and Affiliations
Hulya Tosun Yildirim
Keywords
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