Malignant Fibrous Histiocytoma with Giant Cell: A Cytological, Histopathological and Immunohistochemical Study of A Rare Differential
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 7
Abstract
Malignant Fibrous histiocytoma (MFH) is now diagnosis of exclusion, comprising <5% of adult soft tissue malignant lesion. MFH predominantly is originating from extremities and retroperitoneum. Uncommon presentation can be in chest wall, bone, spermatic cord and other organs. As other malignant soft tissue tumour; histologically mimics MFH, hence immunohistochemistry (IHC) is essential for final diagnosis. The IHC findings revealed strong positive staining for CD68 and negative staining for SMA, CD34. The patient was managed by wide margin surgery followed by radiotherapy. He was disease free when followed up for a year. Although MFH of the chest wall is rare, however it must be considered as a differential diagnosis of chest wall tumours.
Authors and Affiliations
M. A. Muzaffar
Keywords
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