Malignant melanoma with bone marrow metastasis and hemophagocytic syndrome
Journal Title: Αρχεία Ελληνικής Ιατρικής - Year 2011, Vol 28, Issue 2
Abstract
A 31-year-old woman with a medical history of metastatic malignant disease involving the liver and the lungs, was admitted in our clinic due to malaise and fatigue that were rapidly deteriorated. Physical examination revealed skin and conjunctival pallor and sinus tachycardia, as well as an enlarged, nodular, hard, non-tender liver, without splenomegaly. The complete blood count showed a normochromic, normocytic anemia, leucopenia and a profound thrombocytopenia (tab. 1). Examination of the peripheral blood smear confirmed the results of the complete blood count and showed a slight left shift of the white blood cells. The biochemical profile was notable for a pronounced increase of the serum LD H and ferritin (tab. 1). A bone marrow aspiration was performed. Pictures 1 to 4 show the bone marrow smear of the patient at high magnification.
Authors and Affiliations
P. DIAMANTOPOULOS, O. BENOPOULOU, S. BOUROS, I. TSIFIS, A. VAMBAKOUSIS, H. GOGAS, J. MELETIS
Keywords
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