Malignant Transformation of Intracranial Epidermoid Cyst to Squamous Cell Carcinoma, Case Report and Literature Review
Journal Title: International Journal of Surgery & Surgical Techniques - Year 2022, Vol 6, Issue 2
Abstract
Intracranial Epidermoid cysts (ECs) are rare, benign tumor of central nervous system that appears from maintain ectodermal implants. Malignant transformation of an EC to squamous-cell carcinoma (SCC) is rarely reported. Intracranial squamous cell carcinoma has known as a poor prognosis condition that optimal modalities remain uncertain. We present the case of 43-years old male complained 3 months severe headache and right eye hemianopia. Primary evaluation depicted right homogenous brain mass which was successfully totally removed. Pathological assessment found epidermoid cyst without any sign of malignancy. Six months later, patient was referred with episodes of intermittent headache and right eye blindness. After initial imaging, new tumor was growth in same site of frontal epidermoid cyst. Second surgery was performed and pathological report discloses to be a malignant SCC. SCC transformation was confirmed by two expert neuro- pathologists. The exact underlying mechanism causing malignant transformation is not definitely known and it seems SCC may have been transformed due to chronic inflammatory respond to epidermoid cyst. Literature reviews demonstrate that, although, optimal total resection in addition adjuvant radiotherapy is the recommended management of choice, patient’s general survival of this condition is generally poor and long-term follow-up is important.
Authors and Affiliations
Farajirad M1*, Farajirad E2 and Torabi S1
Keywords
Related Articles
- EP ID EP747456
- DOI 10.23880/ijsst-16000170
- Views 3
- Downloads 0
Are Nodular Goiter Patients Previously Treated with L-Thyroxine have Unfavorable Outcomes after Surgery Compared to Patients without Medical Treatment?
This systematic review aimed to analyze the literature on PubMed Database regarding studies which compare the patient’s post-thyroidectomy outcomes, between those who were treated with L-Thyroxine prior to surgery and t...
Closure of Abdominal Incisions Following Laparotomy for Peritonitis in Children Primary Closure or Delayed Primary Closure
Background: There is need to determine the optimal management strategy for dirty abdominal surgical wounds. The aim of this study was to evaluate the post-operative wound complications in children whose dirty surgical w...
Malignant Transformation of Intracranial Epidermoid Cyst to Squamous Cell Carcinoma, Case Report and Literature Review
Intracranial Epidermoid cysts (ECs) are rare, benign tumor of central nervous system that appears from maintain ectodermal implants. Malignant transformation of an EC to squamous-cell carcinoma (SCC) is rarely reported....
Radiation Cholecystitis: A Diagnosis to Be Considered
Radiation cholecystitis is an uncommon biliary complication after yttrium -90 radio-embolization. The incidence of radiation cholecystitis is almost 1 % after radio-embolization. The spectrum of this complication can...
The Management of Digestive Neuroendocrine Tumors: About 10 Cases
Objective: Digestive neuroendocrine tumors (NET) are a rare entity of neoplasia that represents 1% of digestive tumors, characterized by a heterogeneous biological, morphological, and clinical presentation. The aim of o...