Mammography Screening in Benign Breast Disease for Risk Stratification of Malignancy
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 12
Abstract
Abstract Breast cancer is the most common female cancer worldwide. Although the widespread use of mammography screening has increased diagnosis of benign breast disease, no specific recommendations have been made for surveillance, except for women with atypias, who are usually recommended to undergo surgical excision. With the current advances in reporting by the use of BI-RADS, the standardization is achieved, but its accuracy in terms of histological correlation remains unanswered. This study will try to establish the same and also aid in improving the management of patients. Correlation between mammographic screening and histopathology among patients clinically diagnosed as benign breast disease were assessed for determining the accuracy of BI-RAD system mammography. On approval of Institutional Ethical Committee, 100 women between the age group 30-70 years were enrolled after obtaining written informed consent. Mammogram had100% sensitivity (95%CI=95.77, 100), 87% positive predictive value (95% CI=79.02, 92.24) and 87% diagnostic accuracy (95% CI=79.02, 92.24) as a screening tool in this study, which was statistically significant. Thirty-one to forty years age group constituted maximum percentage (65%), followed by 41-50 years (21%), >50 years age group (9%), 30 years (5%). Mean ± SD being 39.27 ± 7.22years. Majority of the women were multigravida (56%) and have breastfed baby (94%), which is statistically significant (p=0.001 and p= 0.005 respectively) using Pearson Chi-square test. Upper outer quadrant (35%) was the most common site of breast lump followed by lower inner (22.6%), upper inner (20.2%), central (11.7%) and lower outer (10.5%), which was statistically significant using Chi-square test (p=0.044). Three percentage mother and 1% sister had positive history of breast malignancy, which positively correlated with high-risk benign breast disease.
Authors and Affiliations
Dr Siddarth Ragupathi
Keywords
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