Management of Congenital Afibrinogenemia: Report of Two Cases
Journal Title: Clinical Medical Reviews and Case Reports - Year 2017, Vol 4, Issue 12
Abstract
Fibrinogen (Factor I) is an essential factor in the coagulation cascade. The activation of prothrombin to thrombin by Factor X is followed by the activation of fibrinogen. In turn, thrombin converts fibrinogen to fibrin, which is the end target of both extrinsic and intrinsic pathways. A deficiency in fibrinogen results in the tendency to bleed.
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- EP ID EP272566
- DOI 10.23937/2378-3656/1410196
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