Mapping of transcription factor binding Region of kappa casein (CSN3) gene in Iranian Bacterianus and Dromedaries camels
Journal Title: International journal of Advanced Biological and Biomedical Research - Year 2014, Vol 2, Issue 5
Abstract
κ-casein is a glycosilated protein in mammalian milk that plays an essential role in the milk micelles. Control of κ-casein expression reflects this essential role, although an understanding of the mechanisms involved lags behind that of the other milk protein genes. Transcriptional regulation, a first mechanism for controlling the development of organisms, is carried out by transcription factors binding sites (TFBSs). We determined the 5’ region for Iranian Dromedaries and bactrianus camel κ-casein gene. We also determine their regulatory TFBSs regions. This region contained 14 potential TFBSs The four of them C/EBP-α, Oct1, MGF/STAT5 and TPB have almost perfectly conserved.
Authors and Affiliations
A. A. Khabiri| Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran, M. Tahmoorespur| Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran, M. R. Nassiri| Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran, M. H. Sekhavati| Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran
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