Mapping of transcription factor binding Region of kappa casein (CSN3) gene in Iranian Bacterianus and Dromedaries camels

Abstract

κ-casein is a glycosilated protein in mammalian milk that plays an essential role in the milk micelles. Control of κ-casein expression reflects this essential role, although an understanding of the mechanisms involved lags behind that of the other milk protein genes. Transcriptional regulation, a first mechanism for controlling the development of organisms, is carried out by transcription factors binding sites (TFBSs). We determined the 5’ region for Iranian Dromedaries and bactrianus camel κ-casein gene. We also determine their regulatory TFBSs regions. This region contained 14 potential TFBSs The four of them C/EBP-α, Oct1, MGF/STAT5 and TPB have almost perfectly conserved.

Authors and Affiliations

A. A. Khabiri| Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran, M. Tahmoorespur| Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran, M. R. Nassiri| Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran, M. H. Sekhavati| Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran

Keywords

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  • EP ID EP13257
  • DOI -
  • Views 324
  • Downloads 11

How To Cite

A. A. Khabiri, M. Tahmoorespur, M. R. Nassiri, M. H. Sekhavati (2014). Mapping of transcription factor binding Region of kappa casein (CSN3) gene in Iranian Bacterianus and Dromedaries camels. International journal of Advanced Biological and Biomedical Research, 2(5), 1726-1733. https://europub.co.uk/articles/-A-13257