MaPSeq, A Service-Oriented Architecture for Genomics Research within an Academic Biomedical Research Institution
Journal Title: Informatics - Year 2015, Vol 2, Issue 3
Abstract
Genomics research presents technical, computational, and analytical challenges that are well recognized. Less recognized are the complex sociological, psychological, cultural, and political challenges that arise when genomics research takes place within a large, decentralized academic institution. In this paper, we describe a Service-Oriented Architecture (SOA)—MaPSeq—that was conceptualized and designed to meet the diverse and evolving computational workflow needs of genomics researchers at our large, hospital-affiliated, academic research institution. We present the institutional challenges that motivated the design of MaPSeq before describing the architecture and functionality of MaPSeq. We then discuss SOA solutions and conclude that approaches such as MaPSeq enable efficient and effective computational workflow execution for genomics research and for any type of academic biomedical research that requires complex, computationally-intense workflows.
Authors and Affiliations
Jason Reilly, Stanley Ahalt, John McGee, Phillips Owen, Charles Schmitt and Kirk Wilhelmsen
Multiple-Criteria Decision Support for a Sustainable Supply Chain: Applications to the Fashion Industry
With increasing globalization and international cooperation, the importance of sustainability management across supply chains has received much attention by companies across various industries. Companies therefore stri...
A Recommender System for Programming Online Judges Using Fuzzy Information Modeling
Programming online judges (POJs) are an emerging application scenario in e-learning recommendation areas. Specifically, they are e-learning tools usually used in programming practices for the automatic evaluation of so...
TOPCAT: Desktop Exploration of Tabular Data for Astronomy and Beyond
TOPCAT, the Tool for OPerations on Catalogues And Tables, is an interactive desktop application for retrieval, analysis and manipulation of tabular data, offering a powerful and flexible range of interactive visualizat...
Back-Off Time Calculation Algorithms in WSN
In a Mobile Wireless Sensor Mesh Network (MWSMN), based on the IEEE 802.15.4 standard, low power consumption is vitally important since the network devices are mostly battery driven. This is especially true for devices...
Theory and Practice in Digital Behaviour Change: A Matrix Framework for the Co-Production of Digital Services That Engage, Empower and Emancipate Marginalised People Living with Complex and Chronic Conditions
Background: The WHO framework on integrated people-centred health services promotes a focus on the needs of people and their communities to empower them to have a more active role in their own health. It has advocated...